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• W1987956240 abstract "Neurofibromatosis 1 occurs in 2 to 3 people per 10,000. The most frequent clinical features are café-au-lait macules, neurofibromas, intertriginous freckling, Lisch nodules, and learning disabilities, but optic and other gliomas, malignant peripheral nerve sheath tumors, and characteristic osseous lesions also can be present. Two striking aspects of neurofibromatosis 1 are its progressive nature and its extreme variability. This article reviews the natural history and some important clinical manifestations of neurofibromatosis 1, with emphasis on features that constitute the standard diagnostic criteria. The pathogenic implications of these clinical manifestations are also considered." @default.
• W1987956240 created "2016-06-24" @default.
• W1987956240 creator A5009535533 @default.
• W1987956240 date "2002-08-01" @default.
• W1987956240 modified "2023-10-14" @default.
• W1987956240 title "Review Article : Neurofibromatosis 1: Clinical Manifestations and Diagnostic Criteria" @default.
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• W1987956240 doi "https://doi.org/10.1177/088307380201700802" @default.
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