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- W1988044554 abstract "Abstract Cognitive deficits are one of the most common non-motor symptoms of Parkinson's disease (PD). Mild cognitive impairment (MCI) affects about 27% of non-demented PD patients. The high prevalence of PD-MCI and PD with dementia (PD-D) as well as increasing life expectancy in PD creates the need for valid serial cognitive assessment in every PD clinic. In this paper we discuss the PD-MCI criteria and testing recommendations (Movement Disorder Society Task Force Guidelines) in the context of referral for neuropsychological assessment in clinical practice. The methodology suggested in the PD-MCI diagnosis guidelines is compared against PD-D testing recommendations. The requirement for at least 10 cognitive tests to allow PD-MCI subtype to be determined is questioned, as a direct correspondence between low scores on a particular test and a domain-specific deficit cannot be assumed. As a variety of factors may underlie an impaired test score, the same test score may be affected by different deficits in different patients (e.g. a low verbal fluency score may be due to executive or language decline). A pathway approach to PD-MCI diagnosis is presented, inline with PD-D diagnostic guidelines. In cases where thorough screening results and clinical history are consistent with each other and presentation seems typical for PD-MCI, level I diagnosis could be established without neuropsychological assessment. However, when screening results diverge from the clinical history or the presentation is atypical, neuropsychological assessment should precede the diagnostic formulation." @default.
- W1988044554 created "2016-06-24" @default.
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- W1988044554 date "2014-12-01" @default.
- W1988044554 modified "2023-09-26" @default.
- W1988044554 title "Mild cognitive impairment in Parkinson's disease: How much testing is needed for correct diagnosis?" @default.
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- W1988044554 doi "https://doi.org/10.1016/j.baga.2014.06.001" @default.
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