Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988050051> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1988050051 endingPage "114" @default.
- W1988050051 startingPage "106" @default.
- W1988050051 abstract "The goal of this study was to confirm the effectiveness of our novel treatment strategy, neoadjuvant therapy (NAT) consisting of combined chemo- and radiotherapy, which are performed before complete excision of residual tumor in patients with intracranial nongerminomatous malignant germ cell tumors (NGMGCTs).The authors treated 11 consecutive patients with NGMGCTs by applying NAT consisting of combined platinum-based chemotherapy and radiotherapy, followed by complete excision of residual tumors. The pretreatment diagnosis, based on tumor markers with or without biopsy, was yolk sac tumor in five patients, embryonal carcinoma in one patient, immature teratoma in one patient, and mixed germ cell tumor containing malignant tumor components in four patients. Among the 11 patients, NAT achieved a complete response in two and a partial response in six patients; two patients manifested no change and one suffered disease progression. Residual tumors that occurred post-NAT were surgically removed in nine patients. Of the 11 patients, 10 are currently alive without recurrence of their disease, 30 to 177 months (mean 96 months) after diagnosis. In one patient a leptomeningeal tumor recurred and he died of the disease 21 months after diagnosis.Neoadjuvant therapy, consisting of combined chemo- and radiotherapy, followed by complete excision of residual tumors is highly effective in patients with intracranial NGMGCTs." @default.
- W1988050051 created "2016-06-24" @default.
- W1988050051 creator A5000923412 @default.
- W1988050051 creator A5009672923 @default.
- W1988050051 creator A5011914841 @default.
- W1988050051 creator A5017377538 @default.
- W1988050051 creator A5038115951 @default.
- W1988050051 creator A5050922395 @default.
- W1988050051 date "2003-07-01" @default.
- W1988050051 modified "2023-10-02" @default.
- W1988050051 title "Successful treatment of intracranial nongerminomatous malignant germ cell tumors by administering neoadjuvant chemotherapy and radiotherapy before excision of residual tumors" @default.
- W1988050051 cites W2274992595 @default.
- W1988050051 doi "https://doi.org/10.3171/jns.2003.99.1.0106" @default.
- W1988050051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12854751" @default.
- W1988050051 hasPublicationYear "2003" @default.
- W1988050051 type Work @default.
- W1988050051 sameAs 1988050051 @default.
- W1988050051 citedByCount "78" @default.
- W1988050051 countsByYear W19880500512012 @default.
- W1988050051 countsByYear W19880500512013 @default.
- W1988050051 countsByYear W19880500512014 @default.
- W1988050051 countsByYear W19880500512015 @default.
- W1988050051 countsByYear W19880500512016 @default.
- W1988050051 countsByYear W19880500512017 @default.
- W1988050051 countsByYear W19880500512018 @default.
- W1988050051 countsByYear W19880500512019 @default.
- W1988050051 countsByYear W19880500512020 @default.
- W1988050051 countsByYear W19880500512021 @default.
- W1988050051 countsByYear W19880500512022 @default.
- W1988050051 crossrefType "journal-article" @default.
- W1988050051 hasAuthorship W1988050051A5000923412 @default.
- W1988050051 hasAuthorship W1988050051A5009672923 @default.
- W1988050051 hasAuthorship W1988050051A5011914841 @default.
- W1988050051 hasAuthorship W1988050051A5017377538 @default.
- W1988050051 hasAuthorship W1988050051A5038115951 @default.
- W1988050051 hasAuthorship W1988050051A5050922395 @default.
- W1988050051 hasBestOaLocation W19880500511 @default.
- W1988050051 hasConcept C121608353 @default.
- W1988050051 hasConcept C126322002 @default.
- W1988050051 hasConcept C126838900 @default.
- W1988050051 hasConcept C141071460 @default.
- W1988050051 hasConcept C196843134 @default.
- W1988050051 hasConcept C2775934546 @default.
- W1988050051 hasConcept C2776694085 @default.
- W1988050051 hasConcept C2776938808 @default.
- W1988050051 hasConcept C2777043721 @default.
- W1988050051 hasConcept C2778292576 @default.
- W1988050051 hasConcept C509974204 @default.
- W1988050051 hasConcept C530470458 @default.
- W1988050051 hasConcept C71924100 @default.
- W1988050051 hasConcept C86803240 @default.
- W1988050051 hasConcept C95444343 @default.
- W1988050051 hasConceptScore W1988050051C121608353 @default.
- W1988050051 hasConceptScore W1988050051C126322002 @default.
- W1988050051 hasConceptScore W1988050051C126838900 @default.
- W1988050051 hasConceptScore W1988050051C141071460 @default.
- W1988050051 hasConceptScore W1988050051C196843134 @default.
- W1988050051 hasConceptScore W1988050051C2775934546 @default.
- W1988050051 hasConceptScore W1988050051C2776694085 @default.
- W1988050051 hasConceptScore W1988050051C2776938808 @default.
- W1988050051 hasConceptScore W1988050051C2777043721 @default.
- W1988050051 hasConceptScore W1988050051C2778292576 @default.
- W1988050051 hasConceptScore W1988050051C509974204 @default.
- W1988050051 hasConceptScore W1988050051C530470458 @default.
- W1988050051 hasConceptScore W1988050051C71924100 @default.
- W1988050051 hasConceptScore W1988050051C86803240 @default.
- W1988050051 hasConceptScore W1988050051C95444343 @default.
- W1988050051 hasIssue "1" @default.
- W1988050051 hasLocation W19880500511 @default.
- W1988050051 hasLocation W19880500512 @default.
- W1988050051 hasOpenAccess W1988050051 @default.
- W1988050051 hasPrimaryLocation W19880500511 @default.
- W1988050051 hasRelatedWork W1988050051 @default.
- W1988050051 hasRelatedWork W2075825929 @default.
- W1988050051 hasRelatedWork W2152396131 @default.
- W1988050051 hasRelatedWork W2380415970 @default.
- W1988050051 hasRelatedWork W2404042595 @default.
- W1988050051 hasRelatedWork W2411506775 @default.
- W1988050051 hasRelatedWork W2412908548 @default.
- W1988050051 hasRelatedWork W2462459542 @default.
- W1988050051 hasRelatedWork W1928008527 @default.
- W1988050051 hasRelatedWork W52282236 @default.
- W1988050051 hasVolume "99" @default.
- W1988050051 isParatext "false" @default.
- W1988050051 isRetracted "false" @default.
- W1988050051 magId "1988050051" @default.
- W1988050051 workType "article" @default.