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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988053589> ?p ?o ?g. }

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• W1988053589 abstract "A series of 9 homoserine lactone-derived sulfonylureas substituted by an alkyl chain, some of them bearing a phenyl group at the extremity, have been prepared. All compounds were found to inhibit the action of 3-oxo-hexanoyl-L-homoserine lactone, the natural inducer of bioluminescence in the bacterium Vibrio fischeri, the aliphatic compounds being more active than their phenyl-substituted counterparts. Molecular modelling studies performed on the most active compound in each series suggest that the antagonist activity could be related to the perturbation of the hydrogen-bond network in the ligand-protein complexes." @default.
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• W1988053589 date "2008-04-01" @default.
• W1988053589 modified "2023-10-17" @default.
• W1988053589 title "Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator" @default.
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• W1988053589 doi "https://doi.org/10.1016/j.bmc.2008.02.023" @default.
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