Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988062436> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1988062436 endingPage "725" @default.
- W1988062436 startingPage "719" @default.
- W1988062436 abstract "Purpose. To investigate possible causes and implications of the decrease in glutathione concentration in rat lenses during organ culture.Methods. Freshly excised lenses were incubated in modified TC-199 medium. Ellman's Reagent or the GSH-400 assay were used to assay glutathione levels in lenses cultured for different times and under a variety of altered culture conditions.Results. In lenses from young rats the glutathione decrease was not ameliorated by reduction of oxygen tension in the incubator, nor by supplementation of the culture medium with various antioxidants or sulfhydryl compounds, nor with the amino acid precursors of glutathione. Addition of 2-mercaptoethanol stimulated cysteine transport into the lens but had only a modest effect in maintaining the level of glutathione. The decrease in glutathione concentration was less in cultured lenses from older rats. Lenses from rhesus monkeys exhibited no decrease in glutathione levels when maintained in organ culture for up to 48 h.Conclusions. The basis for the decreased glutathione in cultured young rat lenses is still uncertain. The data from the present study indicate a definite relationship between glutathione loss and age for cultured rat lenses, with young lenses being much more susceptible. The resistance of cultured monkey lenses to loss of glutathione demonstrates species differences in this property which may be relevant to previously reported differences in susceptibility to oxidative damage." @default.
- W1988062436 created "2016-06-24" @default.
- W1988062436 creator A5021192876 @default.
- W1988062436 creator A5050181905 @default.
- W1988062436 creator A5052522653 @default.
- W1988062436 creator A5069672297 @default.
- W1988062436 creator A5085702059 @default.
- W1988062436 date "1996-01-01" @default.
- W1988062436 modified "2023-10-16" @default.
- W1988062436 title "Investigations into the loss of glutathione from lenses" @default.
- W1988062436 cites W1970059329 @default.
- W1988062436 cites W1972070256 @default.
- W1988062436 cites W1983945262 @default.
- W1988062436 cites W1987013731 @default.
- W1988062436 cites W1994402749 @default.
- W1988062436 cites W1998441660 @default.
- W1988062436 cites W2008312758 @default.
- W1988062436 cites W2010224381 @default.
- W1988062436 cites W2010994708 @default.
- W1988062436 cites W2016524437 @default.
- W1988062436 cites W2028743693 @default.
- W1988062436 cites W2034554948 @default.
- W1988062436 cites W2041365012 @default.
- W1988062436 cites W2041769533 @default.
- W1988062436 cites W2055838346 @default.
- W1988062436 cites W2062703434 @default.
- W1988062436 cites W2070038624 @default.
- W1988062436 cites W2071153095 @default.
- W1988062436 cites W2077479423 @default.
- W1988062436 cites W2088586454 @default.
- W1988062436 cites W2089110523 @default.
- W1988062436 cites W2154235553 @default.
- W1988062436 cites W2158150851 @default.
- W1988062436 cites W2167807668 @default.
- W1988062436 cites W4240530114 @default.
- W1988062436 cites W69612348 @default.
- W1988062436 doi "https://doi.org/10.3109/02713689609003454" @default.
- W1988062436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8670779" @default.
- W1988062436 hasPublicationYear "1996" @default.
- W1988062436 type Work @default.
- W1988062436 sameAs 1988062436 @default.
- W1988062436 citedByCount "13" @default.
- W1988062436 countsByYear W19880624362013 @default.
- W1988062436 countsByYear W19880624362018 @default.
- W1988062436 countsByYear W19880624362019 @default.
- W1988062436 crossrefType "journal-article" @default.
- W1988062436 hasAuthorship W1988062436A5021192876 @default.
- W1988062436 hasAuthorship W1988062436A5050181905 @default.
- W1988062436 hasAuthorship W1988062436A5052522653 @default.
- W1988062436 hasAuthorship W1988062436A5069672297 @default.
- W1988062436 hasAuthorship W1988062436A5085702059 @default.
- W1988062436 hasConcept C147789679 @default.
- W1988062436 hasConcept C151730666 @default.
- W1988062436 hasConcept C15336307 @default.
- W1988062436 hasConcept C181199279 @default.
- W1988062436 hasConcept C185592680 @default.
- W1988062436 hasConcept C202751555 @default.
- W1988062436 hasConcept C2776151105 @default.
- W1988062436 hasConcept C2779201268 @default.
- W1988062436 hasConcept C28483552 @default.
- W1988062436 hasConcept C40875361 @default.
- W1988062436 hasConcept C538909803 @default.
- W1988062436 hasConcept C55493867 @default.
- W1988062436 hasConcept C86803240 @default.
- W1988062436 hasConceptScore W1988062436C147789679 @default.
- W1988062436 hasConceptScore W1988062436C151730666 @default.
- W1988062436 hasConceptScore W1988062436C15336307 @default.
- W1988062436 hasConceptScore W1988062436C181199279 @default.
- W1988062436 hasConceptScore W1988062436C185592680 @default.
- W1988062436 hasConceptScore W1988062436C202751555 @default.
- W1988062436 hasConceptScore W1988062436C2776151105 @default.
- W1988062436 hasConceptScore W1988062436C2779201268 @default.
- W1988062436 hasConceptScore W1988062436C28483552 @default.
- W1988062436 hasConceptScore W1988062436C40875361 @default.
- W1988062436 hasConceptScore W1988062436C538909803 @default.
- W1988062436 hasConceptScore W1988062436C55493867 @default.
- W1988062436 hasConceptScore W1988062436C86803240 @default.
- W1988062436 hasIssue "7" @default.
- W1988062436 hasLocation W19880624361 @default.
- W1988062436 hasLocation W19880624362 @default.
- W1988062436 hasOpenAccess W1988062436 @default.
- W1988062436 hasPrimaryLocation W19880624361 @default.
- W1988062436 hasRelatedWork W1581167643 @default.
- W1988062436 hasRelatedWork W1964971555 @default.
- W1988062436 hasRelatedWork W1965312928 @default.
- W1988062436 hasRelatedWork W1983972257 @default.
- W1988062436 hasRelatedWork W2093143336 @default.
- W1988062436 hasRelatedWork W2275597726 @default.
- W1988062436 hasRelatedWork W2313488920 @default.
- W1988062436 hasRelatedWork W2332213720 @default.
- W1988062436 hasRelatedWork W4200160080 @default.
- W1988062436 hasRelatedWork W4210443329 @default.
- W1988062436 hasVolume "15" @default.
- W1988062436 isParatext "false" @default.
- W1988062436 isRetracted "false" @default.
- W1988062436 magId "1988062436" @default.
- W1988062436 workType "article" @default.