Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988077881> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1988077881 abstract "Adhesion differences between cell populations are in principle a source of strong morphogenetic forces promoting cell sorting, boundary formation and tissue positioning, and cadherins are main mediators of cell adhesion. However, a direct link between cadherin expression, differential adhesion and morphogenesis has not yet been determined for a specific process in vivo. To identify such a connection, we modulated the expression of C-cadherin in the Xenopus laevis gastrula, and combined this with direct measurements of cell adhesion-related parameters. Our results show that gastrulation is surprisingly tolerant of overall changes in adhesion. Also, as expected, experimentally generated, cadherin-based adhesion differences promote cell sorting in vitro. Importantly, however, such differences do not lead to the sorting of cells in the embryo, showing that differential adhesion is not sufficient to drive morphogenesis in this system. Compensatory recruitment of cadherin protein to contacts between cadherin-deprived and -overexpressing cells could contribute to the prevention of sorting in vivo." @default.
- W1988077881 created "2016-06-24" @default.
- W1988077881 creator A5018084804 @default.
- W1988077881 creator A5026841023 @default.
- W1988077881 creator A5065959212 @default.
- W1988077881 creator A5067514769 @default.
- W1988077881 creator A5068298171 @default.
- W1988077881 creator A5082557444 @default.
- W1988077881 date "2012-07-01" @default.
- W1988077881 modified "2023-09-27" @default.
- W1988077881 title "Cadherin-dependent differential cell adhesion in Xenopus causes cell sorting in vitro but not in the embryo" @default.
- W1988077881 cites W2169826619 @default.
- W1988077881 doi "https://doi.org/10.1242/dev.084764" @default.
- W1988077881 hasPublicationYear "2012" @default.
- W1988077881 type Work @default.
- W1988077881 sameAs 1988077881 @default.
- W1988077881 citedByCount "0" @default.
- W1988077881 crossrefType "journal-article" @default.
- W1988077881 hasAuthorship W1988077881A5018084804 @default.
- W1988077881 hasAuthorship W1988077881A5026841023 @default.
- W1988077881 hasAuthorship W1988077881A5065959212 @default.
- W1988077881 hasAuthorship W1988077881A5067514769 @default.
- W1988077881 hasAuthorship W1988077881A5068298171 @default.
- W1988077881 hasAuthorship W1988077881A5082557444 @default.
- W1988077881 hasConcept C104317684 @default.
- W1988077881 hasConcept C129536746 @default.
- W1988077881 hasConcept C1491633281 @default.
- W1988077881 hasConcept C149402561 @default.
- W1988077881 hasConcept C16224149 @default.
- W1988077881 hasConcept C178790620 @default.
- W1988077881 hasConcept C185592680 @default.
- W1988077881 hasConcept C196843134 @default.
- W1988077881 hasConcept C2778630268 @default.
- W1988077881 hasConcept C2779535977 @default.
- W1988077881 hasConcept C40692019 @default.
- W1988077881 hasConcept C54355233 @default.
- W1988077881 hasConcept C84416704 @default.
- W1988077881 hasConcept C85789140 @default.
- W1988077881 hasConcept C86803240 @default.
- W1988077881 hasConcept C87073359 @default.
- W1988077881 hasConcept C95444343 @default.
- W1988077881 hasConceptScore W1988077881C104317684 @default.
- W1988077881 hasConceptScore W1988077881C129536746 @default.
- W1988077881 hasConceptScore W1988077881C1491633281 @default.
- W1988077881 hasConceptScore W1988077881C149402561 @default.
- W1988077881 hasConceptScore W1988077881C16224149 @default.
- W1988077881 hasConceptScore W1988077881C178790620 @default.
- W1988077881 hasConceptScore W1988077881C185592680 @default.
- W1988077881 hasConceptScore W1988077881C196843134 @default.
- W1988077881 hasConceptScore W1988077881C2778630268 @default.
- W1988077881 hasConceptScore W1988077881C2779535977 @default.
- W1988077881 hasConceptScore W1988077881C40692019 @default.
- W1988077881 hasConceptScore W1988077881C54355233 @default.
- W1988077881 hasConceptScore W1988077881C84416704 @default.
- W1988077881 hasConceptScore W1988077881C85789140 @default.
- W1988077881 hasConceptScore W1988077881C86803240 @default.
- W1988077881 hasConceptScore W1988077881C87073359 @default.
- W1988077881 hasConceptScore W1988077881C95444343 @default.
- W1988077881 hasLocation W19880778811 @default.
- W1988077881 hasOpenAccess W1988077881 @default.
- W1988077881 hasPrimaryLocation W19880778811 @default.
- W1988077881 hasRelatedWork W1548085266 @default.
- W1988077881 hasRelatedWork W1572557579 @default.
- W1988077881 hasRelatedWork W1991797784 @default.
- W1988077881 hasRelatedWork W1998442976 @default.
- W1988077881 hasRelatedWork W2020036304 @default.
- W1988077881 hasRelatedWork W2026292627 @default.
- W1988077881 hasRelatedWork W2051296058 @default.
- W1988077881 hasRelatedWork W2092032317 @default.
- W1988077881 hasRelatedWork W2094016360 @default.
- W1988077881 hasRelatedWork W2129232821 @default.
- W1988077881 hasRelatedWork W2169826619 @default.
- W1988077881 hasRelatedWork W2208352238 @default.
- W1988077881 hasRelatedWork W2403908084 @default.
- W1988077881 hasRelatedWork W2410641979 @default.
- W1988077881 hasRelatedWork W2593320416 @default.
- W1988077881 hasRelatedWork W2969741173 @default.
- W1988077881 hasRelatedWork W3161603037 @default.
- W1988077881 hasRelatedWork W3167390221 @default.
- W1988077881 hasRelatedWork W49060787 @default.
- W1988077881 hasRelatedWork W2131077365 @default.
- W1988077881 isParatext "false" @default.
- W1988077881 isRetracted "false" @default.
- W1988077881 magId "1988077881" @default.
- W1988077881 workType "article" @default.