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• W1988080421 abstract "Furanfurin (2-beta-D-ribofuranosylfuran-4-carboxamide) derivatives and analogues were synthesized and their affinity for adenosine receptors was determined. The agonistic behavior of furanfurin against A1 receptors is preserved only when the furan ring is substituted with isosteric pentatomic ring systems such as oxazole, thiazole or thiophene, and the carboxamide group is unsubstituted. Replacement of the hydrogen atoms of the carboxamide group with alkyl, cycloalkyl or arylalkyl groups generates compounds endowed with moderate antagonistic activity." @default.
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• W1988080421 date "2000-09-01" @default.
• W1988080421 modified "2023-10-03" @default.
• W1988080421 title "c-nucleoside analogues of furanfurin as ligands to a1 adenosine receptors" @default.
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• W1988080421 doi "https://doi.org/10.1016/s0968-0896(00)00167-x" @default.
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