FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988147130> ?p ?o ?g. }

• W1988147130 endingPage "622" @default.
• W1988147130 startingPage "619" @default.
• W1988147130 abstract "The proliferative response of murine lymphocytes to interleukin-2 (IL-2) was examined under physico-chemical conditions present in solid tumours, namely low oxygen and glucose concentrations and acidic pH. Lymphocytes were cultured for four days in 30 U ml-1 IL-2 to simulate serum IL-2 concentrations attainable with high-dose systemic IL-2 therapy. Lymphocyte proliferation was significantly (P < 0.05) reduced by low oxygen concentrations (both anoxia [0% O2] and hypoxia [10%, low glucose (6 mg dl-1), or acidic pH (6.7 or 6.4). Moderate glucose concentration (32 mg dl-1), or neutral pH (7.0) did not impair proliferation. This study indicates that impairment of lymphocyte proliferation by tumour physico-chemical conditions may be a factor in the relatively poor success rate of IL-2/LAK cell immunotherapy." @default.
• W1988147130 created "2016-06-24" @default.
• W1988147130 creator A5005636139 @default.
• W1988147130 creator A5044656211 @default.
• W1988147130 creator A5046236312 @default.
• W1988147130 date "1992-10-01" @default.
• W1988147130 modified "2023-10-06" @default.
• W1988147130 title "Influence of tumour physico-chemical conditions on interleukin-2-stimulated lymphocyte proliferation" @default.
• W1988147130 cites W145871740 @default.
• W1988147130 cites W1480346895 @default.
• W1988147130 cites W1533626451 @default.
• W1988147130 cites W1575778999 @default.
• W1988147130 cites W1577567970 @default.
• W1988147130 cites W1588519773 @default.
• W1988147130 cites W167451947 @default.
• W1988147130 cites W1744024959 @default.
• W1988147130 cites W1754823593 @default.
• W1988147130 cites W1885963261 @default.
• W1988147130 cites W1956944003 @default.
• W1988147130 cites W1971672446 @default.
• W1988147130 cites W1990625116 @default.
• W1988147130 cites W2041698198 @default.
• W1988147130 cites W2049822454 @default.
• W1988147130 cites W2065828669 @default.
• W1988147130 cites W2130537353 @default.
• W1988147130 cites W2133243467 @default.
• W1988147130 cites W2141809626 @default.
• W1988147130 cites W2143300952 @default.
• W1988147130 cites W2157607856 @default.
• W1988147130 cites W2322553446 @default.
• W1988147130 cites W2339838622 @default.
• W1988147130 cites W2406505455 @default.
• W1988147130 cites W2405293128 @default.
• W1988147130 doi "https://doi.org/10.1038/bjc.1992.326" @default.
• W1988147130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1977437" @default.
• W1988147130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1419598" @default.
• W1988147130 hasPublicationYear "1992" @default.
• W1988147130 type Work @default.
• W1988147130 sameAs 1988147130 @default.
• W1988147130 citedByCount "65" @default.
• W1988147130 countsByYear W19881471302012 @default.
• W1988147130 countsByYear W19881471302013 @default.
• W1988147130 countsByYear W19881471302014 @default.
• W1988147130 countsByYear W19881471302015 @default.
• W1988147130 countsByYear W19881471302016 @default.
• W1988147130 countsByYear W19881471302018 @default.
• W1988147130 countsByYear W19881471302019 @default.
• W1988147130 countsByYear W19881471302021 @default.
• W1988147130 countsByYear W19881471302022 @default.
• W1988147130 countsByYear W19881471302023 @default.
• W1988147130 crossrefType "journal-article" @default.
• W1988147130 hasAuthorship W1988147130A5005636139 @default.
• W1988147130 hasAuthorship W1988147130A5044656211 @default.
• W1988147130 hasAuthorship W1988147130A5046236312 @default.
• W1988147130 hasBestOaLocation W19881471302 @default.
• W1988147130 hasConcept C126322002 @default.
• W1988147130 hasConcept C134018914 @default.
• W1988147130 hasConcept C178790620 @default.
• W1988147130 hasConcept C185592680 @default.
• W1988147130 hasConcept C203014093 @default.
• W1988147130 hasConcept C2776090121 @default.
• W1988147130 hasConcept C2777371288 @default.
• W1988147130 hasConcept C2777701055 @default.
• W1988147130 hasConcept C2777761686 @default.
• W1988147130 hasConcept C2778690821 @default.
• W1988147130 hasConcept C2778740727 @default.
• W1988147130 hasConcept C540031477 @default.
• W1988147130 hasConcept C55493867 @default.
• W1988147130 hasConcept C62112901 @default.
• W1988147130 hasConcept C71924100 @default.
• W1988147130 hasConcept C74172505 @default.
• W1988147130 hasConcept C7836513 @default.
• W1988147130 hasConcept C86803240 @default.
• W1988147130 hasConcept C8891405 @default.
• W1988147130 hasConceptScore W1988147130C126322002 @default.
• W1988147130 hasConceptScore W1988147130C134018914 @default.
• W1988147130 hasConceptScore W1988147130C178790620 @default.
• W1988147130 hasConceptScore W1988147130C185592680 @default.
• W1988147130 hasConceptScore W1988147130C203014093 @default.
• W1988147130 hasConceptScore W1988147130C2776090121 @default.
• W1988147130 hasConceptScore W1988147130C2777371288 @default.
• W1988147130 hasConceptScore W1988147130C2777701055 @default.
• W1988147130 hasConceptScore W1988147130C2777761686 @default.
• W1988147130 hasConceptScore W1988147130C2778690821 @default.
• W1988147130 hasConceptScore W1988147130C2778740727 @default.
• W1988147130 hasConceptScore W1988147130C540031477 @default.
• W1988147130 hasConceptScore W1988147130C55493867 @default.
• W1988147130 hasConceptScore W1988147130C62112901 @default.
• W1988147130 hasConceptScore W1988147130C71924100 @default.
• W1988147130 hasConceptScore W1988147130C74172505 @default.
• W1988147130 hasConceptScore W1988147130C7836513 @default.
• W1988147130 hasConceptScore W1988147130C86803240 @default.
• W1988147130 hasConceptScore W1988147130C8891405 @default.
• W1988147130 hasIssue "4" @default.
• W1988147130 hasLocation W19881471301 @default.
• W1988147130 hasLocation W19881471302 @default.
• W1988147130 hasLocation W19881471303 @default.
• W1988147130 hasLocation W19881471304 @default.

• next