FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988156677> ?p ?o ?g. }

• W1988156677 endingPage "4370" @default.
• W1988156677 startingPage "4361" @default.
• W1988156677 abstract "We describe a new type of aptamer-based optical nanosensor which uses the embedding of target responsive oligonucleotides in porous polyacrylamide nanoparticles to eliminate nuclease instability. The latter is a common problem in the use of aptamer sensors in biological environments. These aptamers embedded in nanoparticles (AptaNPs) are proposed as a tool in real-time metabolite measurements in living cells. The AptaNPs comprise 30 nm polyacrylamide nanoparticles, prepared by inverse microemulsion polymerization, which contain water-soluble aptamer switch probes (ASPs) trapped in the porous matrix of the nanoparticles. The matrix acts as a molecular fence allowing rapid diffusion of small metabolites into the particles to interact with the aptamer molecules, but at the same time it retains the larger aptamer molecules inside the nanoparticles providing protection against intracellular degradation. We tested the ability of the AptaNPs to measure the adenine-nucleotide content in yeast cells. Our results successfully demonstrate the potential for monitoring any metabolite of interest in living cells by selecting specific aptamers and embedding them in nanoparticles." @default.
• W1988156677 created "2016-06-24" @default.
• W1988156677 creator A5019113973 @default.
• W1988156677 creator A5065193496 @default.
• W1988156677 creator A5068328382 @default.
• W1988156677 date "2010-07-22" @default.
• W1988156677 modified "2023-10-10" @default.
• W1988156677 title "Aptamers Embedded in Polyacrylamide Nanoparticles: A Tool for <i>in Vivo</i> Metabolite Sensing" @default.
• W1988156677 cites W1775749144 @default.
• W1988156677 cites W1963650109 @default.
• W1988156677 cites W1970478438 @default.
• W1988156677 cites W1973911001 @default.
• W1988156677 cites W1974729836 @default.
• W1988156677 cites W1978539997 @default.
• W1988156677 cites W1986486963 @default.
• W1988156677 cites W1987565198 @default.
• W1988156677 cites W1988556506 @default.
• W1988156677 cites W1993478813 @default.
• W1988156677 cites W2000990429 @default.
• W1988156677 cites W2010635656 @default.
• W1988156677 cites W2016431195 @default.
• W1988156677 cites W2022012719 @default.
• W1988156677 cites W2025483591 @default.
• W1988156677 cites W2031089624 @default.
• W1988156677 cites W2033570693 @default.
• W1988156677 cites W2042081776 @default.
• W1988156677 cites W2043872789 @default.
• W1988156677 cites W2048846190 @default.
• W1988156677 cites W2056789539 @default.
• W1988156677 cites W2061530854 @default.
• W1988156677 cites W2065601399 @default.
• W1988156677 cites W2066282687 @default.
• W1988156677 cites W2068185820 @default.
• W1988156677 cites W2079063862 @default.
• W1988156677 cites W2079321730 @default.
• W1988156677 cites W2085619806 @default.
• W1988156677 cites W2092808634 @default.
• W1988156677 cites W2104525153 @default.
• W1988156677 cites W2106150629 @default.
• W1988156677 cites W2137458512 @default.
• W1988156677 cites W2138668121 @default.
• W1988156677 cites W2138733854 @default.
• W1988156677 cites W2158888617 @default.
• W1988156677 cites W2160572948 @default.
• W1988156677 cites W2164730913 @default.
• W1988156677 cites W2170679909 @default.
• W1988156677 cites W2171439027 @default.
• W1988156677 cites W2331706143 @default.
• W1988156677 cites W4247747034 @default.
• W1988156677 cites W4295192894 @default.
• W1988156677 doi "https://doi.org/10.1021/nn100635j" @default.
• W1988156677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20731422" @default.
• W1988156677 hasPublicationYear "2010" @default.
• W1988156677 type Work @default.
• W1988156677 sameAs 1988156677 @default.
• W1988156677 citedByCount "89" @default.
• W1988156677 countsByYear W19881566772012 @default.
• W1988156677 countsByYear W19881566772013 @default.
• W1988156677 countsByYear W19881566772014 @default.
• W1988156677 countsByYear W19881566772015 @default.
• W1988156677 countsByYear W19881566772016 @default.
• W1988156677 countsByYear W19881566772017 @default.
• W1988156677 countsByYear W19881566772018 @default.
• W1988156677 countsByYear W19881566772019 @default.
• W1988156677 countsByYear W19881566772020 @default.
• W1988156677 countsByYear W19881566772021 @default.
• W1988156677 countsByYear W19881566772022 @default.
• W1988156677 countsByYear W19881566772023 @default.
• W1988156677 crossrefType "journal-article" @default.
• W1988156677 hasAuthorship W1988156677A5019113973 @default.
• W1988156677 hasAuthorship W1988156677A5065193496 @default.
• W1988156677 hasAuthorship W1988156677A5068328382 @default.
• W1988156677 hasConcept C12554922 @default.
• W1988156677 hasConcept C128972844 @default.
• W1988156677 hasConcept C129312508 @default.
• W1988156677 hasConcept C153911025 @default.
• W1988156677 hasConcept C155672457 @default.
• W1988156677 hasConcept C171250308 @default.
• W1988156677 hasConcept C185592680 @default.
• W1988156677 hasConcept C188027245 @default.
• W1988156677 hasConcept C192562407 @default.
• W1988156677 hasConcept C2778862431 @default.
• W1988156677 hasConcept C41858301 @default.
• W1988156677 hasConcept C552990157 @default.
• W1988156677 hasConcept C55493867 @default.
• W1988156677 hasConcept C86803240 @default.
• W1988156677 hasConceptScore W1988156677C12554922 @default.
• W1988156677 hasConceptScore W1988156677C128972844 @default.
• W1988156677 hasConceptScore W1988156677C129312508 @default.
• W1988156677 hasConceptScore W1988156677C153911025 @default.
• W1988156677 hasConceptScore W1988156677C155672457 @default.
• W1988156677 hasConceptScore W1988156677C171250308 @default.
• W1988156677 hasConceptScore W1988156677C185592680 @default.
• W1988156677 hasConceptScore W1988156677C188027245 @default.
• W1988156677 hasConceptScore W1988156677C192562407 @default.
• W1988156677 hasConceptScore W1988156677C2778862431 @default.
• W1988156677 hasConceptScore W1988156677C41858301 @default.
• W1988156677 hasConceptScore W1988156677C552990157 @default.

• next