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- W1988165989 abstract "Because heat shock proteins (HSPs) have an important protective function against ischemia/anoxia in mammalian brain, the authors investigated the expression of Hsp72 and Hsc73 in the anoxia-surviving turtle brain. Unlike the mammalian brain, high levels of Hsp72 were found in the normoxic turtle brain. Hsp72 levels were significantly increased by 4 hours of anoxia, remained constant until 8 hours, and then decreased to baseline at 12 hours. By contrast, Hsc73 was progressively increased throughout 12 hours of anoxia. This differential expression suggests different protective roles: Hsp72 in the initial downregulatory transition phase, and Hsc73 in maintaining neural network integrity during the long-term hypometabolic phase." @default.
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- W1988165989 date "2004-07-01" @default.
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- W1988165989 title "The Upregulation of Cognate and Inducible Heat Shock Proteins in the Anoxic Turtle Brain" @default.
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- W1988165989 doi "https://doi.org/10.1097/01.wcb.0000126565.27130.79" @default.
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