FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988179473> ?p ?o ?g. }

• W1988179473 endingPage "L155" @default.
• W1988179473 startingPage "L145" @default.
• W1988179473 abstract "Multiple K + channels are expressed in the respiratory epithelium lining airways and alveoli. Of the three main classes [ 1) voltage-dependent or Ca 2+ -activated, 6-transmembrane domains (TMD), 2) 2-pores 4-TMD, and 3) inward-rectified 2-TMD K + channels], almost 40 different transcripts have already been detected in the lung. The physiological and functional significance of this high molecular diversity of lung epithelial K + channels is intriguing. As detailed in the present review, K + channels are located at both the apical and basolateral membranes in the respiratory epithelium, where they mediate K + currents of diverse electrophysiological and regulatory properties. The main recognized function of K + channels is to control membrane potential and to maintain the driving force for transepithelial ion and liquid transport. In this manner, KvLQT1, KCa and K ATP channels, for example, contribute to the control of airway and alveolar surface liquid composition and volume. Thus, K + channel activation has been identified as a potential therapeutic strategy for the resolution of pathologies characterized by ion transport dysfunction. K + channels are also involved in other key functions in lung physiology, such as oxygen-sensing, inflammatory responses and respiratory epithelia repair after injury. The purpose of this review is to summarize and discuss what is presently known about the molecular identity of lung K + channels with emphasis on their role in lung epithelial physiology." @default.
• W1988179473 created "2016-06-24" @default.
• W1988179473 creator A5061482906 @default.
• W1988179473 creator A5087609231 @default.
• W1988179473 creator A5089052304 @default.
• W1988179473 date "2009-02-01" @default.
• W1988179473 modified "2023-10-15" @default.
• W1988179473 title "Molecular diversity and function of K⁺ channels in airway and alveolar epithelial cells" @default.
• W1988179473 cites W179490056 @default.
• W1988179473 cites W1900482019 @default.
• W1988179473 cites W1963813734 @default.
• W1988179473 cites W1967880298 @default.
• W1988179473 cites W1969802354 @default.
• W1988179473 cites W1971861592 @default.
• W1988179473 cites W1972279565 @default.
• W1988179473 cites W1972882396 @default.
• W1988179473 cites W1973161876 @default.
• W1988179473 cites W1973279448 @default.
• W1988179473 cites W1975453079 @default.
• W1988179473 cites W1977495203 @default.
• W1988179473 cites W1978241980 @default.
• W1988179473 cites W1980642677 @default.
• W1988179473 cites W1991033228 @default.
• W1988179473 cites W1991662012 @default.
• W1988179473 cites W1991894493 @default.
• W1988179473 cites W1992432080 @default.
• W1988179473 cites W1993000646 @default.
• W1988179473 cites W1993611145 @default.
• W1988179473 cites W1994169475 @default.
• W1988179473 cites W1996423471 @default.
• W1988179473 cites W1998222784 @default.
• W1988179473 cites W1998971453 @default.
• W1988179473 cites W1999274391 @default.
• W1988179473 cites W1999398013 @default.
• W1988179473 cites W2000819593 @default.
• W1988179473 cites W2001182901 @default.
• W1988179473 cites W2007520808 @default.
• W1988179473 cites W2010739912 @default.
• W1988179473 cites W2012228357 @default.
• W1988179473 cites W2013782505 @default.
• W1988179473 cites W2014073666 @default.
• W1988179473 cites W2014827728 @default.
• W1988179473 cites W2015873509 @default.
• W1988179473 cites W2018840519 @default.
• W1988179473 cites W2024033984 @default.
• W1988179473 cites W2027379754 @default.
• W1988179473 cites W2032487666 @default.
• W1988179473 cites W2038833704 @default.
• W1988179473 cites W2040348197 @default.
• W1988179473 cites W2046829224 @default.
• W1988179473 cites W2047230464 @default.
• W1988179473 cites W2051040059 @default.
• W1988179473 cites W2051577737 @default.
• W1988179473 cites W2055372624 @default.
• W1988179473 cites W2056663194 @default.
• W1988179473 cites W2062793852 @default.
• W1988179473 cites W2064821447 @default.
• W1988179473 cites W2065044742 @default.
• W1988179473 cites W2067133157 @default.
• W1988179473 cites W2073371442 @default.
• W1988179473 cites W2079894038 @default.
• W1988179473 cites W2081798670 @default.
• W1988179473 cites W2088146700 @default.
• W1988179473 cites W2093087513 @default.
• W1988179473 cites W2094441194 @default.
• W1988179473 cites W2099587101 @default.
• W1988179473 cites W2102048637 @default.
• W1988179473 cites W2105364078 @default.
• W1988179473 cites W2107362126 @default.
• W1988179473 cites W2107567984 @default.
• W1988179473 cites W2112538037 @default.
• W1988179473 cites W2115802065 @default.
• W1988179473 cites W2117692193 @default.
• W1988179473 cites W2119337400 @default.
• W1988179473 cites W2120675235 @default.
• W1988179473 cites W2125713628 @default.
• W1988179473 cites W2131118533 @default.
• W1988179473 cites W2132789315 @default.
• W1988179473 cites W2132941372 @default.
• W1988179473 cites W2140463015 @default.
• W1988179473 cites W2143070723 @default.
• W1988179473 cites W2143391760 @default.
• W1988179473 cites W2146142858 @default.
• W1988179473 cites W2148635587 @default.
• W1988179473 cites W2151310499 @default.
• W1988179473 cites W2152622855 @default.
• W1988179473 cites W2153268980 @default.
• W1988179473 cites W2158465267 @default.
• W1988179473 cites W2162300941 @default.
• W1988179473 cites W2166804935 @default.
• W1988179473 cites W2174651279 @default.
• W1988179473 cites W2181507124 @default.
• W1988179473 cites W2255042896 @default.
• W1988179473 cites W2274304862 @default.
• W1988179473 cites W2317264807 @default.
• W1988179473 cites W4233719888 @default.
• W1988179473 cites W81433057 @default.
• W1988179473 doi "https://doi.org/10.1152/ajplung.90525.2008" @default.

• next