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- W1988179677 abstract "Genetic factors might be involved in stroke prognosis, however the role of brain-derived neurotrophic factor (BDNF) in stroke recovery is unknown. We have studied BDNF −196 G>A and −270 C>T polymorphisms in ischemic and hemorrhagic stroke and their impact on stroke prognosis. There was higher occurrence of BDNF −270 CC genotype in patients with hemorrhagic than ischemic stroke (96% versus 86%, p=0.0495). In hemorrhagic stroke BDNF −196 GG carriers scored better in NIHSS at admission (14.23 versus 21.00, p=0.0192) and after 7 days (8.60 versus 15.00, p=0.0408) of onsets. None of the determined polymorphisms had any impact on 30 day early outcome in ischemic and hemorrhagic stroke." @default.
- W1988179677 created "2016-06-24" @default.
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- W1988179677 date "2012-08-01" @default.
- W1988179677 modified "2023-09-26" @default.
- W1988179677 title "BDNF −270 C>T polymorphisms might be associated with stroke type and BDNF −196 G>A corresponds to early neurological deficit in hemorrhagic stroke" @default.
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- W1988179677 doi "https://doi.org/10.1016/j.jneuroim.2012.04.011" @default.
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