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- W1988186204 abstract "The case history is presented of a 75 year old man with chronic asthma who was treated with inhaled fluticasone propionate in a daily dose of 2 mg using a Diskhaler. After three years of treatment he developed progressive hoarseness. Both vocal cords were colonised by<i>Aspergillus fumigatus </i>which formed a white slough on the surface. Biopsy specimens showed changes suggestive of laryngeal aspergillosis with an ulcerated epithelium, fibrinopurulent debris, and colonies of fungal hyphae. A slow recovery occurred after three months of treatment with topical amphotericin and with cessation of inhaled corticosteroids. Laryngoscopy is recommended if hoarseness occurs during treatment with fluticasone." @default.
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- W1988186204 date "1999-09-01" @default.
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- W1988186204 title "Laryngeal aspergillosis following high dose inhaled fluticasone therapy for asthma" @default.
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- W1988186204 doi "https://doi.org/10.1136/thx.54.9.860" @default.
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