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- W1988200269 abstract "The response of F1 hybrid mice to the injection of parental T cells depends upon, among other things, the genetic make up of donor and host. In most cases, inoculation results in the development of lethal graft-versus-host disease in the recipient, but under certain circumstances a condition resembling human lupus erythematosus ensues. According to Charles Via and Gene Shearer, an analysis of these lupus-inducing crosses suggests that disease is the result of a deficient cytotoxic T-cell response that is unable to control the proliferation of autoantibody-producing B cells. A better understanding of these murine model systems may allow the defects behind the human condition to be identified." @default.
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- W1988200269 date "1988-01-01" @default.
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- W1988200269 title "T-cell interactions in autoimmunity" @default.
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- W1988200269 doi "https://doi.org/10.1016/0167-5699(88)91215-7" @default.
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