Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988200410> ?p ?o ?g. }
- W1988200410 endingPage "77" @default.
- W1988200410 startingPage "69" @default.
- W1988200410 abstract "Human G-protein-coupled formyl peptide receptor-like 1 and its mouse homologue formyl peptide receptor 2 mediate the chemotactic activity of a variety of pathogen and host-derived peptides, including amyloid beta(42), a key causative factor in Alzheimer's disease (AD).Here, we found that polyinosine-polycytidylic acid (Poly(I:C)), which is a specific TLR3 ligand, and Imiquimod (R837), which is a specific TLR7 ligand, when used alone, each increased MAPK-dependent functional mFPR2 expression in microglial cells, and the combination of Poly(I:C) and R837 exhibited additive effect by enhancing the level of IkappaB-alpha phosphorylation. Our results indicated that RNA virus infection may actively participate in the pathogenic processes of brain inflammation and neurodegenerative diseases by TLR3- and TLR7-mediated TRIF-dependent and MyD88-dependent signaling pathways." @default.
- W1988200410 created "2016-06-24" @default.
- W1988200410 creator A5000716419 @default.
- W1988200410 creator A5011981086 @default.
- W1988200410 creator A5040885646 @default.
- W1988200410 creator A5060002817 @default.
- W1988200410 creator A5061261246 @default.
- W1988200410 creator A5075003658 @default.
- W1988200410 date "2009-08-18" @default.
- W1988200410 modified "2023-09-27" @default.
- W1988200410 title "Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglial cells" @default.
- W1988200410 cites W1483386514 @default.
- W1988200410 cites W1503511302 @default.
- W1988200410 cites W1544940894 @default.
- W1988200410 cites W1571163061 @default.
- W1988200410 cites W1642883912 @default.
- W1988200410 cites W1969072247 @default.
- W1988200410 cites W1981802408 @default.
- W1988200410 cites W1983218156 @default.
- W1988200410 cites W1993639599 @default.
- W1988200410 cites W1994108614 @default.
- W1988200410 cites W1998211335 @default.
- W1988200410 cites W2013708994 @default.
- W1988200410 cites W2022244055 @default.
- W1988200410 cites W2033058856 @default.
- W1988200410 cites W2036767516 @default.
- W1988200410 cites W2041690090 @default.
- W1988200410 cites W2046770212 @default.
- W1988200410 cites W2047895583 @default.
- W1988200410 cites W2048797077 @default.
- W1988200410 cites W2049449151 @default.
- W1988200410 cites W2052997401 @default.
- W1988200410 cites W2054445727 @default.
- W1988200410 cites W2058567997 @default.
- W1988200410 cites W2066344383 @default.
- W1988200410 cites W2076361525 @default.
- W1988200410 cites W2078811876 @default.
- W1988200410 cites W2079168625 @default.
- W1988200410 cites W2110187123 @default.
- W1988200410 cites W2116096469 @default.
- W1988200410 cites W2116776033 @default.
- W1988200410 cites W2125861763 @default.
- W1988200410 cites W2126906152 @default.
- W1988200410 cites W2129242841 @default.
- W1988200410 cites W2132552167 @default.
- W1988200410 cites W2133500662 @default.
- W1988200410 cites W2141753982 @default.
- W1988200410 cites W2150736048 @default.
- W1988200410 cites W2155965284 @default.
- W1988200410 cites W2163031226 @default.
- W1988200410 cites W2163751922 @default.
- W1988200410 cites W2165257835 @default.
- W1988200410 doi "https://doi.org/10.1016/j.jneuroim.2009.05.018" @default.
- W1988200410 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2761824" @default.
- W1988200410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19559490" @default.
- W1988200410 hasPublicationYear "2009" @default.
- W1988200410 type Work @default.
- W1988200410 sameAs 1988200410 @default.
- W1988200410 citedByCount "15" @default.
- W1988200410 countsByYear W19882004102012 @default.
- W1988200410 countsByYear W19882004102013 @default.
- W1988200410 countsByYear W19882004102019 @default.
- W1988200410 countsByYear W19882004102020 @default.
- W1988200410 countsByYear W19882004102021 @default.
- W1988200410 countsByYear W19882004102023 @default.
- W1988200410 crossrefType "journal-article" @default.
- W1988200410 hasAuthorship W1988200410A5000716419 @default.
- W1988200410 hasAuthorship W1988200410A5011981086 @default.
- W1988200410 hasAuthorship W1988200410A5040885646 @default.
- W1988200410 hasAuthorship W1988200410A5060002817 @default.
- W1988200410 hasAuthorship W1988200410A5061261246 @default.
- W1988200410 hasAuthorship W1988200410A5075003658 @default.
- W1988200410 hasBestOaLocation W19882004102 @default.
- W1988200410 hasConcept C136449434 @default.
- W1988200410 hasConcept C170493617 @default.
- W1988200410 hasConcept C185592680 @default.
- W1988200410 hasConcept C2776709828 @default.
- W1988200410 hasConcept C2778420691 @default.
- W1988200410 hasConcept C2779836521 @default.
- W1988200410 hasConcept C43929388 @default.
- W1988200410 hasConcept C55493867 @default.
- W1988200410 hasConcept C86803240 @default.
- W1988200410 hasConcept C95444343 @default.
- W1988200410 hasConceptScore W1988200410C136449434 @default.
- W1988200410 hasConceptScore W1988200410C170493617 @default.
- W1988200410 hasConceptScore W1988200410C185592680 @default.
- W1988200410 hasConceptScore W1988200410C2776709828 @default.
- W1988200410 hasConceptScore W1988200410C2778420691 @default.
- W1988200410 hasConceptScore W1988200410C2779836521 @default.
- W1988200410 hasConceptScore W1988200410C43929388 @default.
- W1988200410 hasConceptScore W1988200410C55493867 @default.
- W1988200410 hasConceptScore W1988200410C86803240 @default.
- W1988200410 hasConceptScore W1988200410C95444343 @default.
- W1988200410 hasIssue "1-2" @default.
- W1988200410 hasLocation W19882004101 @default.
- W1988200410 hasLocation W19882004102 @default.
- W1988200410 hasLocation W19882004103 @default.
- W1988200410 hasLocation W19882004104 @default.