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• W1988210546 endingPage "551" @default.
• W1988210546 startingPage "545" @default.
• W1988210546 abstract "Purpose of review Bone health is now recognized to contribute to overall lifetime management of children, adolescents, and adults with disabling conditions including physical and intellectual disability and with many chronic disease processes. Such disorders have multiple components, with aspects of care covering a wide number of specialist practices. This review will highlight advances in understanding the nature of bone mass accumulation through childhood and adolescence, the impingement of a spectrum of chronic and disabling diseases and their treatments on bone, and will address current approaches to interpretation of bone mass in the growing skeleton and interventional strategies for improving outcomes for this group. Recent findings Increased skeletal fragility in the disabled child is well recognized. Insights into the contributions of skeletal size and bone strength in males and females have altered interpretation of data, allowing a new focus on determinants of future bone health, particularly with regard to the contributions of growth and puberty. Strategies to address bone health including public and medical education concerning consumption of calcium, appropriate selection of vitamin D preparations, pubertal contribution to phases of growth and possible specialist use of newer drugs, such as bisphosphonates where indicated, are changing the outlook for this large group. Summary Implications of these changed understandings provide a new focus on maximizing bone mass accumulation by the end of adolescence within the constraints of what is possible to achieve for an individual and for provision of an holistic approach to bone health." @default.
• W1988210546 created "2016-06-24" @default.
• W1988210546 creator A5052663341 @default.
• W1988210546 date "2004-10-01" @default.
• W1988210546 modified "2023-10-12" @default.
• W1988210546 title "Current advances in bone health of disabled children" @default.
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• W1988210546 doi "https://doi.org/10.1097/01.mop.0000138679.70932.90" @default.
• W1988210546 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15367849" @default.
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