Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988213948> ?p ?o ?g. }
- W1988213948 endingPage "4501" @default.
- W1988213948 startingPage "4493" @default.
- W1988213948 abstract "We present molecular dynamics simulations of a multicomponent, asymmetric bilayer in mixed aqueous solutions of sodium and potassium chloride. Because of the geometry of the system, there are two aqueous solution regions in our simulations: one mimics the intracellular region, and one mimics the extracellular region. Ion-specific effects are evident at the membrane/aqueous solution interface. Namely, at equal concentrations of sodium and potassium, sodium ions are more strongly adsorbed to carbonyl groups of the lipid headgroups. A significant concentration excess of potassium is needed for this ion to overwhelm the sodium abundance at the membrane. Ion-membrane interactions also lead to concentration-dependent and cation-specific behavior of the electrostatic potential in the intracellular region because of the negative charge on the inner leaflet. In addition, water permeation across the membrane was observed on a timescale of ∼100 ns. This study represents a step toward the modeling of realistic biological membranes at physiological conditions in intracellular and extracellular environments." @default.
- W1988213948 created "2016-06-24" @default.
- W1988213948 creator A5012707599 @default.
- W1988213948 creator A5063109605 @default.
- W1988213948 creator A5065633302 @default.
- W1988213948 date "2009-06-01" @default.
- W1988213948 modified "2023-10-18" @default.
- W1988213948 title "Molecular Model of a Cell Plasma Membrane With an Asymmetric Multicomponent Composition: Water Permeation and Ion Effects" @default.
- W1988213948 cites W1489573754 @default.
- W1988213948 cites W1762647466 @default.
- W1988213948 cites W1964756286 @default.
- W1988213948 cites W1970243421 @default.
- W1988213948 cites W1972800394 @default.
- W1988213948 cites W1973526181 @default.
- W1988213948 cites W1979252698 @default.
- W1988213948 cites W1981021420 @default.
- W1988213948 cites W1981073690 @default.
- W1988213948 cites W1984666622 @default.
- W1988213948 cites W1990316904 @default.
- W1988213948 cites W1999945761 @default.
- W1988213948 cites W2000909010 @default.
- W1988213948 cites W2017525235 @default.
- W1988213948 cites W2017807499 @default.
- W1988213948 cites W2018438417 @default.
- W1988213948 cites W2020103775 @default.
- W1988213948 cites W2025989829 @default.
- W1988213948 cites W2033575799 @default.
- W1988213948 cites W2035911183 @default.
- W1988213948 cites W2036441926 @default.
- W1988213948 cites W2043251868 @default.
- W1988213948 cites W2049183165 @default.
- W1988213948 cites W2049475242 @default.
- W1988213948 cites W2057973387 @default.
- W1988213948 cites W2058102013 @default.
- W1988213948 cites W2059041534 @default.
- W1988213948 cites W2067174909 @default.
- W1988213948 cites W2071581047 @default.
- W1988213948 cites W2072409288 @default.
- W1988213948 cites W2074184542 @default.
- W1988213948 cites W2081260116 @default.
- W1988213948 cites W2090040290 @default.
- W1988213948 cites W2098373224 @default.
- W1988213948 cites W2103945336 @default.
- W1988213948 cites W2118733096 @default.
- W1988213948 cites W2121936687 @default.
- W1988213948 cites W2122745784 @default.
- W1988213948 cites W2123768693 @default.
- W1988213948 cites W2128572087 @default.
- W1988213948 cites W2135268695 @default.
- W1988213948 cites W2155195157 @default.
- W1988213948 cites W2158603948 @default.
- W1988213948 doi "https://doi.org/10.1016/j.bpj.2009.03.010" @default.
- W1988213948 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2711485" @default.
- W1988213948 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19486672" @default.
- W1988213948 hasPublicationYear "2009" @default.
- W1988213948 type Work @default.
- W1988213948 sameAs 1988213948 @default.
- W1988213948 citedByCount "75" @default.
- W1988213948 countsByYear W19882139482012 @default.
- W1988213948 countsByYear W19882139482013 @default.
- W1988213948 countsByYear W19882139482014 @default.
- W1988213948 countsByYear W19882139482015 @default.
- W1988213948 countsByYear W19882139482016 @default.
- W1988213948 countsByYear W19882139482017 @default.
- W1988213948 countsByYear W19882139482018 @default.
- W1988213948 countsByYear W19882139482019 @default.
- W1988213948 countsByYear W19882139482020 @default.
- W1988213948 countsByYear W19882139482021 @default.
- W1988213948 countsByYear W19882139482022 @default.
- W1988213948 countsByYear W19882139482023 @default.
- W1988213948 crossrefType "journal-article" @default.
- W1988213948 hasAuthorship W1988213948A5012707599 @default.
- W1988213948 hasAuthorship W1988213948A5063109605 @default.
- W1988213948 hasAuthorship W1988213948A5065633302 @default.
- W1988213948 hasBestOaLocation W19882139481 @default.
- W1988213948 hasConcept C12554922 @default.
- W1988213948 hasConcept C145148216 @default.
- W1988213948 hasConcept C147597530 @default.
- W1988213948 hasConcept C178790620 @default.
- W1988213948 hasConcept C179104552 @default.
- W1988213948 hasConcept C184651966 @default.
- W1988213948 hasConcept C185592680 @default.
- W1988213948 hasConcept C192157962 @default.
- W1988213948 hasConcept C2778106830 @default.
- W1988213948 hasConcept C28406088 @default.
- W1988213948 hasConcept C39944091 @default.
- W1988213948 hasConcept C41625074 @default.
- W1988213948 hasConcept C50670333 @default.
- W1988213948 hasConcept C517785266 @default.
- W1988213948 hasConcept C537181965 @default.
- W1988213948 hasConcept C55493867 @default.
- W1988213948 hasConcept C59593255 @default.
- W1988213948 hasConcept C79879829 @default.
- W1988213948 hasConcept C86803240 @default.
- W1988213948 hasConceptScore W1988213948C12554922 @default.
- W1988213948 hasConceptScore W1988213948C145148216 @default.
- W1988213948 hasConceptScore W1988213948C147597530 @default.
- W1988213948 hasConceptScore W1988213948C178790620 @default.