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• W1988230824 abstract "Comparar las concentraciones de factor de necrosis tumoral alfa (FNT-alfa) en pacientes con preeclampsia y embarazadas normotensas sanas. Se seleccionó un total de 100 pacientes. Se incluyeron a 50 pacientes preeclámpticas como los casos (grupo A) y un grupo control que fue seleccionado por tener una edad y un índice de masa corporal similares al grupo de estudio, y consistió en 50 embarazadas sanas (grupo B). Las muestras de sangre para la determinación de FNT-alfa se recolectaron en todas las pacientes antes del parto e inmediatamente después del diagnóstico en el grupo de casos. No se encontraron diferencias significativas con relación a la edad materna, edad gestacional e índice de masa corporal al momento de la toma de la muestra (p=ns). Se observaron diferencias estadísticamente significativas entre los grupos en los valores promedio de presión arterial sistólica y diastólica (p<0,05). Se encontraron diferencias estadísticamente significativa en las concentraciones de FNT-alfa entre las pacientes en el grupo A (9,7±4,6 pg/ml) y las pacientes del grupo B (5,5±1,6 pg/ml; p < 0,05) y se observó una correlación moderada, positiva y significativa con los valores de presión arterial sistólica (r=0,433; p < 0,05) y diastólica (r=0,412; p < 0,05). Las preeclámpticas presentaron concentraciones significativamente más altas de FNT-alfa al compararlas con embarazadas normotensas sanas. To compare tumor necrosis factor-alpha concentrations in patients with preeclampsia and healthy normotensive pregnant women. One hundred patients were selected. Fifty preeclamptic patients were selected as cases (group A) and 50 healthy pregnant women with a similar age and body mass index to patients in group A were selected as controls (group B). Blood samples for tumor necrosis factor-alpha determination were collected in all patients before labor and immediately after diagnosis in the study group. There were no significant differences in maternal age, gestational age or body mass index at sample collection (p=ns). Statistically significant differences were found between groups in mean values of systolic and diastolic blood pressure (p < 0.05). Significant differences were found in tumor necrosis factor-alpha concentrations in group A (9.7±4.6 pg/ml) and patients in group B (5.5±1.6 pg/ml; p < 0.05), and a moderate, positive and significant correlation was found with mean systolic (r=0.433; p < 0.05) and diastolic (r=0.412; p < 0.05) blood pressure. Tumor necrosis factor-alpha concentrations were significantly higher in preeclamptic patients than in healthy normotensive pregnant women." @default.
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• W1988230824 date "2012-11-01" @default.
• W1988230824 modified "2023-09-25" @default.
• W1988230824 title "Concentraciones del factor de necrosis tumoral alfa en preeclámpticas y embarazadas normotensas sanas" @default.
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• W1988230824 doi "https://doi.org/10.1016/j.gine.2009.12.014" @default.
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