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- W1988274164 abstract "It has been shown that graded doses of LSD (<i>d</i>-lysergic acid diethylamide-25) produce facilitation of evoked auditory and visual primary responses in the unanesthetized-paralyzed cat. At higher concentrations differential depression of the auditory responses was seen to occur while facilitation of the visual responses could still be detected.<sup>14</sup> The present report extends the observations to include other, nonspecific, afferent pathways and presents evidence relating to the differential action of LSD on various synaptic arrangements. <h3>METHODS</h3> Methods were essentially similar to those reported previously, with the following additions: Recruiting responses were evoked by 5-10/sec. stimulation of the rostral pole of centrum medianum of the thalamus. They were generally recorded maximally from the sensorimotor cortex. Stimuli were delivered through a 0.5 mm. concentric electrode introduced by means of a three-dimensional micro-manipulator. In addition to studying the effect of LSD on cortical potentials evoked from a symmetrical point on one hemisphere" @default.
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- W1988274164 date "1956-02-01" @default.
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- W1988274164 title "Electrophysiological Analysis of Psychotogenic Drug Action" @default.
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- W1988274164 doi "https://doi.org/10.1001/archneurpsyc.1956.02330200026003" @default.
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