Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988297670> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1988297670 endingPage "10" @default.
- W1988297670 startingPage "4" @default.
- W1988297670 abstract "Abstract: The aim was to compare clinical efficacy and safety of two treatment regimens: biphasic insulin aspart (BIAsp) injected at all three meals plus neutral protamine Hagedorn (NPH) insulin at bedtime vs. a human insulin regimen, premixed human insulin at breakfast and soluble insulin at lunch and dinner and NPH at bedtime. A total of 167 adolescents (80 males and 87 females) with type 1 diabetes was included in the trial (multinational, randomized, open-label, and parallel group). Each subject received either of two treatment regimens for a 4-month period. BIAsp was injected immediately before main meals, human insulin products 30 min before meals, and NPH at night. Glycemic control was monitored by eight-point evaluations (after 6 and 16 wks) and hemoglobin A1c (HbA1c) (after 2, 6, and 16 wks). Safety evaluations included adverse events and incidence of hypoglycemic episodes. HbA1c (mean ± SD) after 4 months on BIAsp (9.39 ± 0.14) was not significantly different from that with human insulin (9.30 ± 0.15). The average postprandial glucose increment in the BIAsp group was about half the increment in the human insulin group; the difference not statistically significant. The body mass index (BMI) increased in both groups, but significantly (p = 0.005) less in the BIAsp group. However, in males on BIAsp, the BMI decreased compared with those on human insulin (p = 0.007). No significant group differences were found for the rate of hypoglycemic episodes. We concluded that the BIAsp regimen was associated with similar glycemic control and similar incidence of hypoglycemic episodes as human insulin. However, the BIAsp regimen caused a significantly smaller increase in BMI, particularly in males, compared with the human insulin regimen." @default.
- W1988297670 created "2016-06-24" @default.
- W1988297670 creator A5023087005 @default.
- W1988297670 creator A5041565619 @default.
- W1988297670 creator A5045467957 @default.
- W1988297670 creator A5048161422 @default.
- W1988297670 creator A5059447899 @default.
- W1988297670 creator A5091105571 @default.
- W1988297670 date "2006-02-01" @default.
- W1988297670 modified "2023-10-16" @default.
- W1988297670 title "Biphasic insulin aspart vs. human insulin in adolescents with type 1 diabetes on multiple daily insulin injections" @default.
- W1988297670 cites W1974949976 @default.
- W1988297670 cites W1983304831 @default.
- W1988297670 cites W1993612606 @default.
- W1988297670 cites W2020438483 @default.
- W1988297670 cites W2026952051 @default.
- W1988297670 cites W2049885152 @default.
- W1988297670 cites W2066633683 @default.
- W1988297670 cites W2070315497 @default.
- W1988297670 cites W2075532421 @default.
- W1988297670 cites W2098719472 @default.
- W1988297670 cites W2129121181 @default.
- W1988297670 cites W2133170827 @default.
- W1988297670 cites W2150944713 @default.
- W1988297670 cites W4241385086 @default.
- W1988297670 doi "https://doi.org/10.1111/j.1399-543x.2006.00138.x" @default.
- W1988297670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16489968" @default.
- W1988297670 hasPublicationYear "2006" @default.
- W1988297670 type Work @default.
- W1988297670 sameAs 1988297670 @default.
- W1988297670 citedByCount "24" @default.
- W1988297670 countsByYear W19882976702012 @default.
- W1988297670 countsByYear W19882976702013 @default.
- W1988297670 countsByYear W19882976702014 @default.
- W1988297670 countsByYear W19882976702015 @default.
- W1988297670 countsByYear W19882976702018 @default.
- W1988297670 countsByYear W19882976702020 @default.
- W1988297670 countsByYear W19882976702021 @default.
- W1988297670 countsByYear W19882976702022 @default.
- W1988297670 crossrefType "journal-article" @default.
- W1988297670 hasAuthorship W1988297670A5023087005 @default.
- W1988297670 hasAuthorship W1988297670A5041565619 @default.
- W1988297670 hasAuthorship W1988297670A5045467957 @default.
- W1988297670 hasAuthorship W1988297670A5048161422 @default.
- W1988297670 hasAuthorship W1988297670A5059447899 @default.
- W1988297670 hasAuthorship W1988297670A5091105571 @default.
- W1988297670 hasBestOaLocation W19882976701 @default.
- W1988297670 hasConcept C126322002 @default.
- W1988297670 hasConcept C134018914 @default.
- W1988297670 hasConcept C2777180221 @default.
- W1988297670 hasConcept C2778199505 @default.
- W1988297670 hasConcept C2778537899 @default.
- W1988297670 hasConcept C2778804033 @default.
- W1988297670 hasConcept C2779306644 @default.
- W1988297670 hasConcept C2779908123 @default.
- W1988297670 hasConcept C2779920387 @default.
- W1988297670 hasConcept C2780473172 @default.
- W1988297670 hasConcept C2780668416 @default.
- W1988297670 hasConcept C555293320 @default.
- W1988297670 hasConcept C71924100 @default.
- W1988297670 hasConceptScore W1988297670C126322002 @default.
- W1988297670 hasConceptScore W1988297670C134018914 @default.
- W1988297670 hasConceptScore W1988297670C2777180221 @default.
- W1988297670 hasConceptScore W1988297670C2778199505 @default.
- W1988297670 hasConceptScore W1988297670C2778537899 @default.
- W1988297670 hasConceptScore W1988297670C2778804033 @default.
- W1988297670 hasConceptScore W1988297670C2779306644 @default.
- W1988297670 hasConceptScore W1988297670C2779908123 @default.
- W1988297670 hasConceptScore W1988297670C2779920387 @default.
- W1988297670 hasConceptScore W1988297670C2780473172 @default.
- W1988297670 hasConceptScore W1988297670C2780668416 @default.
- W1988297670 hasConceptScore W1988297670C555293320 @default.
- W1988297670 hasConceptScore W1988297670C71924100 @default.
- W1988297670 hasIssue "1" @default.
- W1988297670 hasLocation W19882976701 @default.
- W1988297670 hasLocation W19882976702 @default.
- W1988297670 hasOpenAccess W1988297670 @default.
- W1988297670 hasPrimaryLocation W19882976701 @default.
- W1988297670 hasRelatedWork W2011084774 @default.
- W1988297670 hasRelatedWork W2080135029 @default.
- W1988297670 hasRelatedWork W2104888919 @default.
- W1988297670 hasRelatedWork W2129737421 @default.
- W1988297670 hasRelatedWork W2153745306 @default.
- W1988297670 hasRelatedWork W2355805719 @default.
- W1988297670 hasRelatedWork W2356435021 @default.
- W1988297670 hasRelatedWork W2371669480 @default.
- W1988297670 hasRelatedWork W2392663985 @default.
- W1988297670 hasRelatedWork W2760509590 @default.
- W1988297670 hasVolume "7" @default.
- W1988297670 isParatext "false" @default.
- W1988297670 isRetracted "false" @default.
- W1988297670 magId "1988297670" @default.
- W1988297670 workType "article" @default.