FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988314386> ?p ?o ?g. }

• W1988314386 endingPage "463" @default.
• W1988314386 startingPage "457" @default.
• W1988314386 abstract "The interplay between vitamin D and IGF-I is complex and occurs at both endocrine and paracrine/autocrine levels. Vitamin D has been shown to increase circulating IGF-I and IGFBP-3, with the consistent finding of a positive correlation between vitamin D and IGF-I serum values in population-based cohorts of healthy subjects. The modulation of IGF-I and IGFBP-3 concentrations by vitamin D may impact recombinant human (rh) GH dosing for the treatment of GHD. It might also underlie some of the extra-skeletal beneficial effects ascribed to vitamin D. On the other hand, IGF-I stimulates renal production of 1,25-dihydroxyvitamin D, which increases calcium and phosphate availability in the body and suppresses PTH secretion. This effect is responsible for an altered calcium-phosphate balance in uncontrolled acromegaly and might also account for the improvement in bone metabolism associated with rhGH treatment in patients with GHD. Data on the paracrine/autocrine vitamin D-IGF-I interactions are abundant, but mostly not linked to one another. As a result, it is not possible to draw a comprehensive picture of the physiological and/or pathological interrelations between vitamin D, IGF-I and IGF-binding proteins (IGFBP) in different tissues. A potential role of vitamin D action is related to its association with carcinogenesis, a paradigm being breast cancer. Current evidence indicates that, in breast tumours, vitamin D modulates the IGF-I/IGFBP ratio to decrease proliferation and increase apoptosis." @default.
• W1988314386 created "2016-06-24" @default.
• W1988314386 creator A5024254071 @default.
• W1988314386 creator A5024849891 @default.
• W1988314386 creator A5026343337 @default.
• W1988314386 creator A5043269563 @default.
• W1988314386 creator A5048037056 @default.
• W1988314386 creator A5062662374 @default.
• W1988314386 date "2013-08-09" @default.
• W1988314386 modified "2023-10-18" @default.
• W1988314386 title "Interactions between vitamin D and IGF-I: from physiology to clinical practice" @default.
• W1988314386 cites W1849648692 @default.
• W1988314386 cites W1873457658 @default.
• W1988314386 cites W1960783300 @default.
• W1988314386 cites W1964479969 @default.
• W1988314386 cites W1965694761 @default.
• W1988314386 cites W1969916031 @default.
• W1988314386 cites W1970730570 @default.
• W1988314386 cites W1971481861 @default.
• W1988314386 cites W1972662184 @default.
• W1988314386 cites W1978131786 @default.
• W1988314386 cites W1991177666 @default.
• W1988314386 cites W1992238227 @default.
• W1988314386 cites W1993569451 @default.
• W1988314386 cites W1994177185 @default.
• W1988314386 cites W1997301608 @default.
• W1988314386 cites W2007320852 @default.
• W1988314386 cites W2011369409 @default.
• W1988314386 cites W2013840081 @default.
• W1988314386 cites W2014798423 @default.
• W1988314386 cites W2018001092 @default.
• W1988314386 cites W2018757284 @default.
• W1988314386 cites W2027895380 @default.
• W1988314386 cites W2036747759 @default.
• W1988314386 cites W2037054135 @default.
• W1988314386 cites W2037749462 @default.
• W1988314386 cites W2040552779 @default.
• W1988314386 cites W2044213834 @default.
• W1988314386 cites W2049426433 @default.
• W1988314386 cites W2054121324 @default.
• W1988314386 cites W2054281547 @default.
• W1988314386 cites W2054391164 @default.
• W1988314386 cites W2054548024 @default.
• W1988314386 cites W2059572231 @default.
• W1988314386 cites W2060347491 @default.
• W1988314386 cites W2068867981 @default.
• W1988314386 cites W2070794097 @default.
• W1988314386 cites W2072419218 @default.
• W1988314386 cites W2075077585 @default.
• W1988314386 cites W2077227904 @default.
• W1988314386 cites W2080747884 @default.
• W1988314386 cites W2081047941 @default.
• W1988314386 cites W2090627812 @default.
• W1988314386 cites W2093854833 @default.
• W1988314386 cites W2099056711 @default.
• W1988314386 cites W2101632387 @default.
• W1988314386 cites W2102979193 @default.
• W1988314386 cites W2103213885 @default.
• W1988314386 cites W2104062693 @default.
• W1988314386 cites W2115391301 @default.
• W1988314386 cites W2117830565 @default.
• W1988314386 cites W2122715907 @default.
• W1988314386 cites W2123317466 @default.
• W1988314386 cites W2124580054 @default.
• W1988314386 cites W2125652724 @default.
• W1988314386 cites W2127573768 @default.
• W1988314386 cites W2129132018 @default.
• W1988314386 cites W2130281902 @default.
• W1988314386 cites W2132096646 @default.
• W1988314386 cites W2135017544 @default.
• W1988314386 cites W2140119451 @default.
• W1988314386 cites W2144378498 @default.
• W1988314386 cites W2159761131 @default.
• W1988314386 cites W2160372568 @default.
• W1988314386 cites W2160779973 @default.
• W1988314386 cites W2161053030 @default.
• W1988314386 cites W2170539169 @default.
• W1988314386 cites W2175961364 @default.
• W1988314386 cites W2184996682 @default.
• W1988314386 cites W2247812590 @default.
• W1988314386 cites W2418569355 @default.
• W1988314386 cites W4232489712 @default.
• W1988314386 cites W4233984730 @default.
• W1988314386 cites W4238755137 @default.
• W1988314386 cites W4240442832 @default.
• W1988314386 cites W4247567304 @default.
• W1988314386 cites W4251027187 @default.
• W1988314386 cites W4251222869 @default.
• W1988314386 cites W95854108 @default.
• W1988314386 doi "https://doi.org/10.1111/cen.12268" @default.
• W1988314386 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23789983" @default.
• W1988314386 hasPublicationYear "2013" @default.
• W1988314386 type Work @default.
• W1988314386 sameAs 1988314386 @default.
• W1988314386 citedByCount "75" @default.
• W1988314386 countsByYear W19883143862013 @default.
• W1988314386 countsByYear W19883143862014 @default.
• W1988314386 countsByYear W19883143862015 @default.

• next