FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988462903> ?p ?o ?g. }

• W1988462903 endingPage "553" @default.
• W1988462903 startingPage "545" @default.
• W1988462903 abstract "The cytochrome P450 (CYP) system is widely distributed across phyla and plays a key role in the metabolism of xenobiotic compounds. However, most studies on CYP system were developed on vertebrates and among invertebrates, gastropod molluscs are rarely used. In this context, ethoxycoumarin-O-deethylase (ECOD), ethoxyresorufin-O-deethylase (EROD), and pentoxyresorufin-O-dealkylase (PROD) activities, which are indirect measurements of CYP system, were characterized in two freshwater gastropod molluscs, Potamopyrgus antipodarum, and Valvata piscinalis, to ascertain their potential interest as biomarkers of exposure to chemicals. Activities were measured using an in vivo non lethal method based on the measurement of formed product (resorufin or hydroxycoumarin). This in vivo assay allowed to measure the three activities in P. antipodarum and two of them (ECOD and PROD) in V. piscinalis. The detection of activities and the optimization of experimental design were carried out first and allowed to measure the selected activities for one individual. The modulation of the detected activities was secondly assessed using a polycyclic aromatic hydrocarbon (Benzo(a)pyrene). Based on this non destructive measurement, effect of BaP exposure could be detected on ECOD and EROD activity in P. antipodarum, as well on PROD activity of V. piscinalis after 96 h of exposure. Such an in vivo assay must be further developed to be valuably used to screen the exposure of gastropod species to CYP inducer chemicals and its consequences in terms of fitness of the organisms and of the population." @default.
• W1988462903 created "2016-06-24" @default.
• W1988462903 creator A5019957498 @default.
• W1988462903 creator A5028991532 @default.
• W1988462903 creator A5046455986 @default.
• W1988462903 creator A5082628013 @default.
• W1988462903 date "2010-11-18" @default.
• W1988462903 modified "2023-10-09" @default.
• W1988462903 title "In vivo indirect measurement of cytochrome P450-associated activities in freshwater gastropod molluscs" @default.
• W1988462903 cites W1977710068 @default.
• W1988462903 cites W1979470516 @default.
• W1988462903 cites W1982585462 @default.
• W1988462903 cites W1996099327 @default.
• W1988462903 cites W1998596395 @default.
• W1988462903 cites W2002969430 @default.
• W1988462903 cites W2009448294 @default.
• W1988462903 cites W2015586486 @default.
• W1988462903 cites W2029598220 @default.
• W1988462903 cites W2029696675 @default.
• W1988462903 cites W2037128425 @default.
• W1988462903 cites W2037639413 @default.
• W1988462903 cites W2042388766 @default.
• W1988462903 cites W2042633800 @default.
• W1988462903 cites W2068523145 @default.
• W1988462903 cites W2068927629 @default.
• W1988462903 cites W2069704428 @default.
• W1988462903 cites W2070039000 @default.
• W1988462903 cites W2077225399 @default.
• W1988462903 cites W2077758075 @default.
• W1988462903 cites W2094765508 @default.
• W1988462903 cites W2104912946 @default.
• W1988462903 cites W2148598942 @default.
• W1988462903 cites W2155063576 @default.
• W1988462903 cites W2162389330 @default.
• W1988462903 cites W2164237288 @default.
• W1988462903 doi "https://doi.org/10.1002/tox.20515" @default.
• W1988462903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19526537" @default.
• W1988462903 hasPublicationYear "2010" @default.
• W1988462903 type Work @default.
• W1988462903 sameAs 1988462903 @default.
• W1988462903 citedByCount "16" @default.
• W1988462903 countsByYear W19884629032012 @default.
• W1988462903 countsByYear W19884629032013 @default.
• W1988462903 countsByYear W19884629032014 @default.
• W1988462903 countsByYear W19884629032015 @default.
• W1988462903 countsByYear W19884629032016 @default.
• W1988462903 countsByYear W19884629032017 @default.
• W1988462903 countsByYear W19884629032019 @default.
• W1988462903 countsByYear W19884629032021 @default.
• W1988462903 countsByYear W19884629032022 @default.
• W1988462903 crossrefType "journal-article" @default.
• W1988462903 hasAuthorship W1988462903A5019957498 @default.
• W1988462903 hasAuthorship W1988462903A5028991532 @default.
• W1988462903 hasAuthorship W1988462903A5046455986 @default.
• W1988462903 hasAuthorship W1988462903A5082628013 @default.
• W1988462903 hasConcept C107872376 @default.
• W1988462903 hasConcept C115346097 @default.
• W1988462903 hasConcept C115448650 @default.
• W1988462903 hasConcept C144024400 @default.
• W1988462903 hasConcept C149923435 @default.
• W1988462903 hasConcept C150903083 @default.
• W1988462903 hasConcept C151730666 @default.
• W1988462903 hasConcept C181199279 @default.
• W1988462903 hasConcept C185592680 @default.
• W1988462903 hasConcept C207001950 @default.
• W1988462903 hasConcept C2777368869 @default.
• W1988462903 hasConcept C2779343474 @default.
• W1988462903 hasConcept C2780252984 @default.
• W1988462903 hasConcept C2908647359 @default.
• W1988462903 hasConcept C33070731 @default.
• W1988462903 hasConcept C526171541 @default.
• W1988462903 hasConcept C55493867 @default.
• W1988462903 hasConcept C62231903 @default.
• W1988462903 hasConcept C86803240 @default.
• W1988462903 hasConcept C90856448 @default.
• W1988462903 hasConceptScore W1988462903C107872376 @default.
• W1988462903 hasConceptScore W1988462903C115346097 @default.
• W1988462903 hasConceptScore W1988462903C115448650 @default.
• W1988462903 hasConceptScore W1988462903C144024400 @default.
• W1988462903 hasConceptScore W1988462903C149923435 @default.
• W1988462903 hasConceptScore W1988462903C150903083 @default.
• W1988462903 hasConceptScore W1988462903C151730666 @default.
• W1988462903 hasConceptScore W1988462903C181199279 @default.
• W1988462903 hasConceptScore W1988462903C185592680 @default.
• W1988462903 hasConceptScore W1988462903C207001950 @default.
• W1988462903 hasConceptScore W1988462903C2777368869 @default.
• W1988462903 hasConceptScore W1988462903C2779343474 @default.
• W1988462903 hasConceptScore W1988462903C2780252984 @default.
• W1988462903 hasConceptScore W1988462903C2908647359 @default.
• W1988462903 hasConceptScore W1988462903C33070731 @default.
• W1988462903 hasConceptScore W1988462903C526171541 @default.
• W1988462903 hasConceptScore W1988462903C55493867 @default.
• W1988462903 hasConceptScore W1988462903C62231903 @default.
• W1988462903 hasConceptScore W1988462903C86803240 @default.
• W1988462903 hasConceptScore W1988462903C90856448 @default.
• W1988462903 hasIssue "6" @default.
• W1988462903 hasLocation W19884629031 @default.
• W1988462903 hasLocation W19884629032 @default.

• next