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- W1988501215 abstract "Abstract Cytochalasin B and D were found to inhibit HVJ (Sendai virus)-induced fusion of Ehrlich ascites tumor cells. Nearly complete inhibition was attained by 4 uM (2 μg/ml) cytochalasin D, whereas cytochalasin B was a less effective inhibitor. The inhibition was largely reversible. Since the transport of 2-deoxy-glucose into the tumor cells was not affected by cytochalasin D (though inhibited by cytochalasin B), the observed inhibition was not related to the effect of the drugs on sugar transport. Instead, it was suggested that the inhibition was due to the action of the drugs on microfilaments. The requirement of ATP for the cell fusion could be explained at least partly by the involvement of microfilaments in the cell fusion process." @default.
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- W1988501215 date "1977-01-01" @default.
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- W1988501215 title "Inhibition of virus-induced fusion of ehrlich ascites tumor cells by cytochalasin B and D" @default.
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- W1988501215 doi "https://doi.org/10.1016/0024-3205(77)90137-0" @default.
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