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• W1988517763 endingPage "18" @default.
• W1988517763 startingPage "11" @default.
• W1988517763 abstract "Injury of axons in the peripheral nervous system (PNS) induces transcription-dependent changes in gene expression and axonal transport that promote effective regeneration by increasing the intrinsic growth state of axons. Regeneration is enhanced in axons re-injured 1–2 weeks after the intrinsic growth state has been increased by such a prior conditioning lesion (CL). The intrinsic growth state does not increase after axons are injured in the mammalian central nervous system (CNS), where they lack the capacity for effective regeneration. Sensory neurons in the dorsal root ganglion (DRG) have two axonal branches that respond differently to injury. Peripheral branches, which are located entirely in the PNS, are capable of effective regeneration. Central branches regenerate in the PNS (i.e., in the dorsal root, which extends from the DRG to the spinal cord), but not in the CNS (i.e., the spinal cord). A CL of peripheral branches increases the intrinsic growth state of central branches in the dorsal columns of the spinal cord, enabling these axons to undergo lengthy regeneration in a segment of peripheral nerve transplanted into the spinal cord (i.e., a peripheral nerve graft). This regeneration does not occur in the absence of a CL. We will examine how changes in gene expression and axonal transport induced by a CL may promote this regeneration." @default.
• W1988517763 created "2016-06-24" @default.
• W1988517763 creator A5077785903 @default.
• W1988517763 date "2010-05-01" @default.
• W1988517763 modified "2023-09-25" @default.
• W1988517763 title "A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons" @default.
• W1988517763 cites W1546586156 @default.
• W1988517763 cites W1548296683 @default.
• W1988517763 cites W1549911944 @default.
• W1988517763 cites W1572293607 @default.
• W1988517763 cites W1595677918 @default.
• W1988517763 cites W1598099146 @default.
• W1988517763 cites W1598343541 @default.
• W1988517763 cites W1655643580 @default.
• W1988517763 cites W1780336900 @default.
• W1988517763 cites W1802434720 @default.
• W1988517763 cites W1928513416 @default.
• W1988517763 cites W1933602774 @default.
• W1988517763 cites W1957246170 @default.
• W1988517763 cites W1963744588 @default.
• W1988517763 cites W1964282467 @default.
• W1988517763 cites W1965901737 @default.
• W1988517763 cites W1967397074 @default.
• W1988517763 cites W1971407845 @default.
• W1988517763 cites W1971756681 @default.
• W1988517763 cites W1972456806 @default.
• W1988517763 cites W1974940638 @default.
• W1988517763 cites W1975139117 @default.
• W1988517763 cites W1979482491 @default.
• W1988517763 cites W1981662243 @default.
• W1988517763 cites W1982647438 @default.
• W1988517763 cites W1982908050 @default.
• W1988517763 cites W1985812526 @default.
• W1988517763 cites W1985864093 @default.
• W1988517763 cites W1986000576 @default.
• W1988517763 cites W1989405733 @default.
• W1988517763 cites W1991557780 @default.
• W1988517763 cites W1992805397 @default.
• W1988517763 cites W1992888811 @default.
• W1988517763 cites W1993527726 @default.
• W1988517763 cites W1993762028 @default.
• W1988517763 cites W1994002190 @default.
• W1988517763 cites W1994736346 @default.
• W1988517763 cites W1996327998 @default.
• W1988517763 cites W2004131962 @default.
• W1988517763 cites W2008094802 @default.
• W1988517763 cites W2010350262 @default.
• W1988517763 cites W2011704559 @default.
• W1988517763 cites W2012864321 @default.
• W1988517763 cites W2014699192 @default.
• W1988517763 cites W2017179873 @default.
• W1988517763 cites W2020858922 @default.
• W1988517763 cites W2021655964 @default.
• W1988517763 cites W2022840078 @default.
• W1988517763 cites W2023150579 @default.
• W1988517763 cites W2025778924 @default.
• W1988517763 cites W2026100132 @default.
• W1988517763 cites W2029268455 @default.
• W1988517763 cites W2030113770 @default.
• W1988517763 cites W2030779596 @default.
• W1988517763 cites W2031316544 @default.
• W1988517763 cites W2032304318 @default.
• W1988517763 cites W2032989272 @default.
• W1988517763 cites W2036950925 @default.
• W1988517763 cites W2038334571 @default.
• W1988517763 cites W2039214355 @default.
• W1988517763 cites W2041206504 @default.
• W1988517763 cites W2051393924 @default.
• W1988517763 cites W2051945956 @default.
• W1988517763 cites W2052496682 @default.
• W1988517763 cites W2052741383 @default.
• W1988517763 cites W2054414357 @default.
• W1988517763 cites W2057502749 @default.
• W1988517763 cites W2062564388 @default.
• W1988517763 cites W2062834772 @default.
• W1988517763 cites W2063627391 @default.
• W1988517763 cites W2065042412 @default.
• W1988517763 cites W2066575706 @default.
• W1988517763 cites W2069249235 @default.
• W1988517763 cites W2072890908 @default.
• W1988517763 cites W2075387470 @default.
• W1988517763 cites W2076274493 @default.
• W1988517763 cites W2077623928 @default.
• W1988517763 cites W2080155952 @default.
• W1988517763 cites W2083916407 @default.
• W1988517763 cites W2090103985 @default.
• W1988517763 cites W2090243659 @default.
• W1988517763 cites W2090305787 @default.
• W1988517763 cites W2090389580 @default.
• W1988517763 cites W2098024573 @default.
• W1988517763 cites W2098718365 @default.
• W1988517763 cites W2099069039 @default.
• W1988517763 cites W2099287762 @default.
• W1988517763 cites W2102883851 @default.
• W1988517763 cites W2107143290 @default.
• W1988517763 cites W2109891277 @default.
• W1988517763 cites W2109936556 @default.
• W1988517763 cites W2110048005 @default.

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