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- W1988520283 abstract "A recently developed technique for in vivo determination of the electrical resistance of vascular endothelium in microvessels was applied to the vessels in a thin frog muscle, m. cutaneus pectoris. The technique consists of injection of current via a glass micropipette into a capillary and measurement of the resulting intra- and extravascular potential profiles with another micropipette placed at various distances from the current source. The theory of Peskoff and Eisenberg (1974) was used to handle the problems arising from distributed extravascular resistances and was experimentally shown to describe the external field satisfactorily. With this extension of one-dimensional cable theory the specific electrical resistance of arterial microvessels was 33 omega cm2 and of venous capillaries 23 omega cm2. The length constants were 135 and 112 micrometers, respectively. If results from arterial and venous vessels are taken together, the ionic permeabilities at 20 degrees C were PNa = 3.9 X 10(-5) cm X s-1, PK = 5.7 X 10(-5) cm X s-1, PCl = 5.9 X 10(-5) cm X s-1 and PHCO3 = 3.4 X 10(-5) cm X s-1. These figures agree with figures for capillary permeability obtained in tracer experiments on whole muscle. The study bridges a gap between single capillary and whole organ techniques with the conclusion that the two different approaches lead to similar results in muscle capillaries." @default.
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- W1988520283 date "1983-04-01" @default.
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- W1988520283 title "Electrical resistance of muscle capillary endothelium" @default.
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- W1988520283 doi "https://doi.org/10.1016/s0006-3495(83)84366-5" @default.
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