Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988544426> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W1988544426 endingPage "2096" @default.
- W1988544426 startingPage "2095" @default.
- W1988544426 abstract "Bacterial meningitis is a medical emergency requiring prompt recognition and evaluation and urgent institution of appropriate antibacterial therapy. The nature of the causative micro-organisms has changed dramatically over time. For example, the introduction and widespread use of the Haemophilus influenzae type b protein-polysaccharide vaccine has reduced the number of cases of H influenzae meningitis in the United States by 94%, and shifted the median age of patients with meningitis from 15 months to 25 years.1 The use of the septa-valent pneumococcal protein-polysaccharide vaccine and of the quadrivalent conjugate vaccine against Neisseria meningitidis will likely have additional significant impact in preventing meningitis.In the early 1900s, meningitis due to H influenzae or Streptococcus pneumoniae was invariably fatal. Mortality dropped to 25–35% for S pneumoniae and 5–10% for H influenzae and N meningitidis meningitis after the introduction of sulfonamides followed by penicillin in the 1930s and 1940s. Empiric treatment regimens employing vancomycin and a third generation cephalosporin came into widespread use in the early 1990s, but have had little additional impact on mortality.2 This failure is not due to inadequate control of bacterial infection, as modern antibiotic regimens sterilize the CSF …" @default.
- W1988544426 created "2016-06-24" @default.
- W1988544426 creator A5083839440 @default.
- W1988544426 date "2008-05-27" @default.
- W1988544426 modified "2023-10-05" @default.
- W1988544426 title "Bacterial meningitis: An urgent need for further progress to reduce mortality and morbidity" @default.
- W1988544426 cites W1966939224 @default.
- W1988544426 cites W1980010510 @default.
- W1988544426 cites W1985640561 @default.
- W1988544426 cites W2075001809 @default.
- W1988544426 cites W2077137971 @default.
- W1988544426 cites W2096888369 @default.
- W1988544426 cites W2156465771 @default.
- W1988544426 cites W2170431908 @default.
- W1988544426 cites W2324125498 @default.
- W1988544426 cites W2376390361 @default.
- W1988544426 doi "https://doi.org/10.1212/01.wnl.0000313158.07093.6a" @default.
- W1988544426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18505990" @default.
- W1988544426 hasPublicationYear "2008" @default.
- W1988544426 type Work @default.
- W1988544426 sameAs 1988544426 @default.
- W1988544426 citedByCount "7" @default.
- W1988544426 countsByYear W19885444262012 @default.
- W1988544426 crossrefType "journal-article" @default.
- W1988544426 hasAuthorship W1988544426A5083839440 @default.
- W1988544426 hasConcept C177713679 @default.
- W1988544426 hasConcept C187212893 @default.
- W1988544426 hasConcept C2781026528 @default.
- W1988544426 hasConcept C3018430615 @default.
- W1988544426 hasConcept C71924100 @default.
- W1988544426 hasConceptScore W1988544426C177713679 @default.
- W1988544426 hasConceptScore W1988544426C187212893 @default.
- W1988544426 hasConceptScore W1988544426C2781026528 @default.
- W1988544426 hasConceptScore W1988544426C3018430615 @default.
- W1988544426 hasConceptScore W1988544426C71924100 @default.
- W1988544426 hasIssue "Issue 22, Part 2" @default.
- W1988544426 hasLocation W19885444261 @default.
- W1988544426 hasLocation W19885444262 @default.
- W1988544426 hasOpenAccess W1988544426 @default.
- W1988544426 hasPrimaryLocation W19885444261 @default.
- W1988544426 hasRelatedWork W2008700437 @default.
- W1988544426 hasRelatedWork W2019104222 @default.
- W1988544426 hasRelatedWork W2075617988 @default.
- W1988544426 hasRelatedWork W2107133212 @default.
- W1988544426 hasRelatedWork W2182533141 @default.
- W1988544426 hasRelatedWork W2286371939 @default.
- W1988544426 hasRelatedWork W2414724338 @default.
- W1988544426 hasRelatedWork W2782396846 @default.
- W1988544426 hasRelatedWork W4206713096 @default.
- W1988544426 hasRelatedWork W4256353252 @default.
- W1988544426 hasVolume "70" @default.
- W1988544426 isParatext "false" @default.
- W1988544426 isRetracted "false" @default.
- W1988544426 magId "1988544426" @default.
- W1988544426 workType "article" @default.