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- W1988556875 abstract "Potassium accumulation associated with outward membrane potassium current was investigated experimentally in Myxicola giant axon. During prolonged voltage-clamp pulses to positive transmembrane potentials, the K+ equilibrium potential may approach zero mV, suggesting massive K+ accumulation outside the axonal membrane to concentrations many-fold higher than those in the bathing medium. The potassium accumulation can be satisfactorily described by a three-compartment model, consisting of the nerve fiber, a restricted physiological periaxonal space and the bulk solution. The average thickness, θ, of the periaxonal space is calculated as 177 ± 59 Å, i.e., comparable to that in the squid, while the permeability coefficient of the external barrier, PKs, was calculated to be (1.4 ± 0.4)•10-4cm/s. These conclusions are well supported by morphological study." @default.
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- W1988556875 date "1985-03-01" @default.
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- W1988556875 title "Significant potassium ion accumulation at the external surface of Myxicola giant axons" @default.
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- W1988556875 doi "https://doi.org/10.1016/0005-2736(85)90236-6" @default.
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