FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988562442> ?p ?o ?g. }

• W1988562442 endingPage "1007" @default.
• W1988562442 startingPage "1002" @default.
• W1988562442 abstract "This study sought to assess the efficacy of oral sotalol for various arrhythmias in pediatric patients and to evaluate the incidence of proarrhythmia and systemic side effects. Sotalol is a beta-adrenergic blocking agent with additional class III antiarrhythmic properties. Experience in pediatric patients is limited. Data concerning the incidence of proarrhythmia in children are lacking. Seventy-one pediatric patients (mean age 7.3 years) with various supraventricular and ventricular tachyarrhythmias were treated with oral sotalol. All the patients were admitted to the hospital for initiation of sotalol therapy. Antiarrhythmic and proarrhythmic effects of sotalol were assessed by daily surface electrocardiograms (ECGs) during the in-hospital phase and by serial Holter monitoring. Sotalol was either completely (27 [66%] of 41 patients) or partially effective (11 [27%] of 41) in 38 (93%) of 41 patients with supraventricular reentrant tachycardias. In patients with atrial flutter predominantly after operation for congenital heart disease, sotalol was effective in 84% of patients (completely in 9 of 19 and partially in 7 of 19). Ventricular tachycardia was completely (3 of 11) or partially (4 of 11) controlled in 64% of children. Proarrhythmia occurred in seven patients (10%) and consisted of symptomatic bradycardia from sinoatrial block and high grade atrioventricular (AV) block, respectively, in two children; asymptomatic high grade AV block in one; torsade de pointes in one; and relevant increased ventricular ectopic activity in three. Proarrhythmia required drug discontinuation in four patients. Mean duration of treatment for all patients was 18 months (range 1 to 40). Sotalol was an effective antiarrhythmic drug for a wide range of pediatric tachyarrhythmias. The considerable number of patients with proarrhythmic effects indicates the need for initiation of treatment on an inpatient basis and close monitoring by serial Holter electrocardiography." @default.
• W1988562442 created "2016-06-24" @default.
• W1988562442 creator A5027037409 @default.
• W1988562442 creator A5044039643 @default.
• W1988562442 creator A5051021391 @default.
• W1988562442 creator A5062744969 @default.
• W1988562442 date "1995-10-01" @default.
• W1988562442 modified "2023-10-17" @default.
• W1988562442 title "Efficacy and proarrhythmia of oral sotalol in pediatric patients" @default.
• W1988562442 cites W1972922119 @default.
• W1988562442 cites W1977474961 @default.
• W1988562442 cites W1982104734 @default.
• W1988562442 cites W1986601949 @default.
• W1988562442 cites W1988678631 @default.
• W1988562442 cites W1994369614 @default.
• W1988562442 cites W1995071804 @default.
• W1988562442 cites W2000751184 @default.
• W1988562442 cites W2018562903 @default.
• W1988562442 cites W2021154108 @default.
• W1988562442 cites W2032435536 @default.
• W1988562442 cites W2037808000 @default.
• W1988562442 cites W2039932832 @default.
• W1988562442 cites W2045816088 @default.
• W1988562442 cites W2052732414 @default.
• W1988562442 cites W2061113567 @default.
• W1988562442 cites W2076892744 @default.
• W1988562442 cites W2079247578 @default.
• W1988562442 cites W2084942160 @default.
• W1988562442 cites W2086938315 @default.
• W1988562442 cites W2088520838 @default.
• W1988562442 cites W2089064329 @default.
• W1988562442 cites W4232353715 @default.
• W1988562442 cites W4322701612 @default.
• W1988562442 doi "https://doi.org/10.1016/0735-1097(95)00268-3" @default.
• W1988562442 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7560592" @default.
• W1988562442 hasPublicationYear "1995" @default.
• W1988562442 type Work @default.
• W1988562442 sameAs 1988562442 @default.
• W1988562442 citedByCount "90" @default.
• W1988562442 countsByYear W19885624422012 @default.
• W1988562442 countsByYear W19885624422013 @default.
• W1988562442 countsByYear W19885624422014 @default.
• W1988562442 countsByYear W19885624422016 @default.
• W1988562442 countsByYear W19885624422017 @default.
• W1988562442 countsByYear W19885624422019 @default.
• W1988562442 countsByYear W19885624422020 @default.
• W1988562442 countsByYear W19885624422021 @default.
• W1988562442 countsByYear W19885624422022 @default.
• W1988562442 crossrefType "journal-article" @default.
• W1988562442 hasAuthorship W1988562442A5027037409 @default.
• W1988562442 hasAuthorship W1988562442A5044039643 @default.
• W1988562442 hasAuthorship W1988562442A5051021391 @default.
• W1988562442 hasAuthorship W1988562442A5062744969 @default.
• W1988562442 hasConcept C118441451 @default.
• W1988562442 hasConcept C126322002 @default.
• W1988562442 hasConcept C164705383 @default.
• W1988562442 hasConcept C2776639339 @default.
• W1988562442 hasConcept C2776934708 @default.
• W1988562442 hasConcept C2777008848 @default.
• W1988562442 hasConcept C2778292772 @default.
• W1988562442 hasConcept C2778557577 @default.
• W1988562442 hasConcept C2778715236 @default.
• W1988562442 hasConcept C2779161974 @default.
• W1988562442 hasConcept C2780074459 @default.
• W1988562442 hasConcept C2780283014 @default.
• W1988562442 hasConcept C42219234 @default.
• W1988562442 hasConcept C71924100 @default.
• W1988562442 hasConceptScore W1988562442C118441451 @default.
• W1988562442 hasConceptScore W1988562442C126322002 @default.
• W1988562442 hasConceptScore W1988562442C164705383 @default.
• W1988562442 hasConceptScore W1988562442C2776639339 @default.
• W1988562442 hasConceptScore W1988562442C2776934708 @default.
• W1988562442 hasConceptScore W1988562442C2777008848 @default.
• W1988562442 hasConceptScore W1988562442C2778292772 @default.
• W1988562442 hasConceptScore W1988562442C2778557577 @default.
• W1988562442 hasConceptScore W1988562442C2778715236 @default.
• W1988562442 hasConceptScore W1988562442C2779161974 @default.
• W1988562442 hasConceptScore W1988562442C2780074459 @default.
• W1988562442 hasConceptScore W1988562442C2780283014 @default.
• W1988562442 hasConceptScore W1988562442C42219234 @default.
• W1988562442 hasConceptScore W1988562442C71924100 @default.
• W1988562442 hasIssue "4" @default.
• W1988562442 hasLocation W19885624421 @default.
• W1988562442 hasLocation W19885624422 @default.
• W1988562442 hasOpenAccess W1988562442 @default.
• W1988562442 hasPrimaryLocation W19885624421 @default.
• W1988562442 hasRelatedWork W1984554833 @default.
• W1988562442 hasRelatedWork W1988562442 @default.
• W1988562442 hasRelatedWork W1988678631 @default.
• W1988562442 hasRelatedWork W2024106848 @default.
• W1988562442 hasRelatedWork W2083470764 @default.
• W1988562442 hasRelatedWork W2144941539 @default.
• W1988562442 hasRelatedWork W2328826835 @default.
• W1988562442 hasRelatedWork W2338150500 @default.
• W1988562442 hasRelatedWork W2405215964 @default.
• W1988562442 hasRelatedWork W2407421851 @default.
• W1988562442 hasVolume "26" @default.
• W1988562442 isParatext "false" @default.

• next