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- W1988564140 abstract "We report the first known seizure after the administration of human diploid cell vaccine (HDCV). Since the introduction of HDCV for rabies in the United States in June 1980, millions of doses have been administered safely. However, there have been numerous accounts of localized, mild systemic, anaphylactic, and neuroparalytic reactions to HDCV.1-4A 14-year-old boy was brought to our emergency department by his parents on the recommendation of the patient's private physician after consultation with the Centers for Disease Control and Prevention and the World Health Organization. The patient had been visiting the Indonesian island of Bali 2 weeks before, where he was bitten on the left knee by a street dog on whose tail he had stepped. Although the event was considered a provoked attack and there have been no reported cases of rabies on that island in more than 8 years, the consulting organizations strongly recommended postexposure prophylaxis in the event the nonquarantined dog was rabid or had arrived from a neighboring island where rabies was found.On presentation to the emergency department, the patient's initial vital signs were blood pressure, 130/69 mm Hg; pulse, 89/minute; respirations, 20/minute; temperature, 36.8°C; and weight, 57.5 kg. His knee wound had healed, and there were no signs of infection. He reported no constitutional or neurologic complaints. He was a normally active and healthy adolescent with no significant family medical history, including history of seizure disorder. The patient had been taking chloroquine phosphate prophylaxis because of his international travel. In addition, he had taken 25 mg of diphenhydramine hydrochloride the night before to help …" @default.
- W1988564140 created "2016-06-24" @default.
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- W1988564140 date "1997-10-01" @default.
- W1988564140 modified "2023-09-24" @default.
- W1988564140 title "An Acute Neurologic Syndrome Temporally Associated With Postexposure Treatment of Rabies" @default.
- W1988564140 cites W2019370627 @default.
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- W1988564140 doi "https://doi.org/10.1542/peds.100.4.720" @default.
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