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- W1988579837 abstract "The hepatocarcinogen 2-acetylaminofluorene is one of the most studied experimental carcinogens. We have shown previously that normal rat hepatocytes accumulate the tumour suppressor p53 after exposure to this compound while preneoplastic rat hepatocytes do not. We suggested that the lack of p53 response may confer a growth advantage on preneoplastic hepatocytes and may be an important factor in hepatic tumor promotion by 2-acetylaminofluorene and other genotoxic compounds." @default.
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- W1988579837 date "2003-08-01" @default.
- W1988579837 modified "2023-09-24" @default.
- W1988579837 title "Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts" @default.
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- W1988579837 doi "https://doi.org/10.1016/s0024-3205(03)00506-x" @default.
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