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• W1988596037 endingPage "814" @default.
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• W1988596037 abstract "Lecithin-cholesterol acyltransferase (LCAT, EC 2.3.1.43) was assayed in vitro in plasma from normal man, rat, rabbit and dog by following the formation of 14C-cholesteryl esters subsequent to labeling the plasma with 14C-cholesterol in vitro. In all species examined, various local anesthetics were found to inhibit LCAT when studied over the concentration range of 1 to 5 mM. The order of inhibition was dibucaine>benzocaine>tetracaine>lidocaine>procaine. Since LCAT activity represents the combined effect of a deacylation step and an esterification step, inhibition of LCAT by local anesthetics could theoretically involve either or both steps." @default.
• W1988596037 created "2016-06-24" @default.
• W1988596037 creator A5055190013 @default.
• W1988596037 creator A5069491495 @default.
• W1988596037 date "1980-10-01" @default.
• W1988596037 modified "2023-09-26" @default.
• W1988596037 title "Lecithin-cholesterol acyltransferase: Inhibition by local anesthetics in plasma from man and experimental animals in vitro" @default.
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• W1988596037 doi "https://doi.org/10.1007/bf02534370" @default.
• W1988596037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7442470" @default.
• W1988596037 hasPublicationYear "1980" @default.
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