FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988596442> ?p ?o ?g. }

• W1988596442 endingPage "2821" @default.
• W1988596442 startingPage "2809" @default.
• W1988596442 abstract "Two different compensatory mechanisms are engaged when the nervous system senses errors during a reaching movement. First, on-line feedback control mechanisms produce in-flight corrections to reduce errors in the on-going movement. Second, these errors modify the internal model with which the motor plan is transformed into motor commands for the subsequent movements. What are the neural mechanisms of these compensatory systems? In a previous study, we reported that while on-line error correction was disturbed in patients with Huntington's disease (HD), it was largely intact in patients with cerebellar degeneration. Here we altered dynamics of reaching and studied the effect of error in one trial on the motor commands that initiated the subsequent trial. We observed that in patients with cerebellar degeneration, motor commands changed from trial-to-trial by an amount that was comparable to control subjects. However, these changes were random and were uninformed by the error in the preceding trial. In contrast, the change in motor commands of HD patients was strongly related to the error in the preceding trial. This error-dependent change had a sensitivity that was comparable to healthy controls. As a result, HD patients exhibited no significant deficits in adapting to novel arm dynamics, whereas cerebellar subjects were profoundly impaired. These results demonstrate a double dissociation between on-line and trial-to-trial error correction suggesting that these compensatory mechanisms have distinct neural bases that can be differentially affected by disease." @default.
• W1988596442 created "2016-06-24" @default.
• W1988596442 creator A5028147110 @default.
• W1988596442 creator A5028793301 @default.
• W1988596442 date "2005-05-01" @default.
• W1988596442 modified "2023-10-17" @default.
• W1988596442 title "Intact Ability to Learn Internal Models of Arm Dynamics in Huntington's Disease But Not Cerebellar Degeneration" @default.
• W1988596442 cites W1509657154 @default.
• W1988596442 cites W1654752245 @default.
• W1988596442 cites W170853314 @default.
• W1988596442 cites W1856925845 @default.
• W1988596442 cites W1873164297 @default.
• W1988596442 cites W1910406166 @default.
• W1988596442 cites W1922715780 @default.
• W1988596442 cites W1976564877 @default.
• W1988596442 cites W1980440818 @default.
• W1988596442 cites W1980910543 @default.
• W1988596442 cites W1987159715 @default.
• W1988596442 cites W1995522314 @default.
• W1988596442 cites W1996990492 @default.
• W1988596442 cites W1997348215 @default.
• W1988596442 cites W1997967772 @default.
• W1988596442 cites W2003263836 @default.
• W1988596442 cites W2004107712 @default.
• W1988596442 cites W2010488120 @default.
• W1988596442 cites W2016148512 @default.
• W1988596442 cites W2022113456 @default.
• W1988596442 cites W2032139276 @default.
• W1988596442 cites W2036685176 @default.
• W1988596442 cites W2038389552 @default.
• W1988596442 cites W2043968544 @default.
• W1988596442 cites W2052582422 @default.
• W1988596442 cites W2053405854 @default.
• W1988596442 cites W2058406815 @default.
• W1988596442 cites W2062676916 @default.
• W1988596442 cites W2066898081 @default.
• W1988596442 cites W2073078656 @default.
• W1988596442 cites W2075864906 @default.
• W1988596442 cites W2076525365 @default.
• W1988596442 cites W2077805044 @default.
• W1988596442 cites W2081817157 @default.
• W1988596442 cites W2088529467 @default.
• W1988596442 cites W2097121325 @default.
• W1988596442 cites W2101187955 @default.
• W1988596442 cites W2106457270 @default.
• W1988596442 cites W2106936397 @default.
• W1988596442 cites W2108136628 @default.
• W1988596442 cites W2108900988 @default.
• W1988596442 cites W2110771795 @default.
• W1988596442 cites W2114999674 @default.
• W1988596442 cites W2119075149 @default.
• W1988596442 cites W2119579955 @default.
• W1988596442 cites W2119697669 @default.
• W1988596442 cites W2138398296 @default.
• W1988596442 cites W2140366636 @default.
• W1988596442 cites W2148101386 @default.
• W1988596442 cites W2166224121 @default.
• W1988596442 cites W2167628560 @default.
• W1988596442 cites W2240997638 @default.
• W1988596442 cites W37898312 @default.
• W1988596442 cites W4298589430 @default.
• W1988596442 cites W79215725 @default.
• W1988596442 doi "https://doi.org/10.1152/jn.00943.2004" @default.
• W1988596442 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15625094" @default.
• W1988596442 hasPublicationYear "2005" @default.
• W1988596442 type Work @default.
• W1988596442 sameAs 1988596442 @default.
• W1988596442 citedByCount "467" @default.
• W1988596442 countsByYear W19885964422012 @default.
• W1988596442 countsByYear W19885964422013 @default.
• W1988596442 countsByYear W19885964422014 @default.
• W1988596442 countsByYear W19885964422015 @default.
• W1988596442 countsByYear W19885964422016 @default.
• W1988596442 countsByYear W19885964422017 @default.
• W1988596442 countsByYear W19885964422018 @default.
• W1988596442 countsByYear W19885964422019 @default.
• W1988596442 countsByYear W19885964422020 @default.
• W1988596442 countsByYear W19885964422021 @default.
• W1988596442 countsByYear W19885964422022 @default.
• W1988596442 countsByYear W19885964422023 @default.
• W1988596442 crossrefType "journal-article" @default.
• W1988596442 hasAuthorship W1988596442A5028147110 @default.
• W1988596442 hasAuthorship W1988596442A5028793301 @default.
• W1988596442 hasBestOaLocation W19885964422 @default.
• W1988596442 hasConcept C102931765 @default.
• W1988596442 hasConcept C107690735 @default.
• W1988596442 hasConcept C137813230 @default.
• W1988596442 hasConcept C142724271 @default.
• W1988596442 hasConcept C147789679 @default.
• W1988596442 hasConcept C154945302 @default.
• W1988596442 hasConcept C15744967 @default.
• W1988596442 hasConcept C169760540 @default.
• W1988596442 hasConcept C185592680 @default.
• W1988596442 hasConcept C2775924081 @default.
• W1988596442 hasConcept C2779134260 @default.
• W1988596442 hasConcept C2779652256 @default.
• W1988596442 hasConcept C2780647506 @default.
• W1988596442 hasConcept C28427503 @default.

• next