Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988603902> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1988603902 endingPage "277" @default.
- W1988603902 startingPage "271" @default.
- W1988603902 abstract "Alterations of estrous cyclicity and ovarian follicles following prenatal exposure to PCB126 were examined. Female SD rats were given (i.g.) 25 pg, 2.5, 250 ng and 7.5 microg of PCB126/kg or the vehicle on days 13-19 postconception. Vaginal opening (VO) in the 250 ng and 7.5 microg offspring was significantly delayed. All groups showed irregular estrous cyclicity following VO, but it became normal after a few days. However, the start of normal estrous cyclicity following VO in the 2.5, 250 ng and 7.5 microg groups was significantly delayed. At 30 and 50 days old, the 2.5, 250 ng and 7.5 microg groups showed significantly fewer antral follicles and a higher number of atretic follicles. The 7.5 microg group at 50 days old revealed significantly fewer corpus luteums. In 50-day-old offspring, the 2.5, 250 ng and 7.5 microg groups showed a significant reduction in serum 17beta-estradiol and progesterone levels and significantly higher levels of PCB126 in the fatty tissue compared with the vehicle group. Thus, while the prenatal dose of PCB126 used in this study did not induce malformation of the external genitalia or persistent ovarian disruption, disruption of ovarian function at puberty was found in the 2.5 ng group of pups born to dams exposed to 17.5 ng/kg PCB126. The present study suggests that PCB126, at least in part, exerted direct effects on the ovary as shown by the disruption of estrous cyclicity." @default.
- W1988603902 created "2016-06-24" @default.
- W1988603902 creator A5007381377 @default.
- W1988603902 creator A5016393150 @default.
- W1988603902 creator A5021339696 @default.
- W1988603902 creator A5030161631 @default.
- W1988603902 creator A5038103250 @default.
- W1988603902 creator A5041204580 @default.
- W1988603902 creator A5059583393 @default.
- W1988603902 date "2003-08-01" @default.
- W1988603902 modified "2023-10-18" @default.
- W1988603902 title "Estrous cyclicity and ovarian follicles in female rats after prenatal exposure to 3,3′,4,4′,5-pentachlorobiphenyl" @default.
- W1988603902 cites W1546668746 @default.
- W1988603902 cites W1972942507 @default.
- W1988603902 cites W1978442608 @default.
- W1988603902 cites W1994405927 @default.
- W1988603902 cites W2011056135 @default.
- W1988603902 cites W2011582760 @default.
- W1988603902 cites W2027143723 @default.
- W1988603902 cites W2049865486 @default.
- W1988603902 cites W2053860818 @default.
- W1988603902 cites W2065733758 @default.
- W1988603902 cites W2066011930 @default.
- W1988603902 cites W2068684749 @default.
- W1988603902 cites W2082589589 @default.
- W1988603902 cites W2091255782 @default.
- W1988603902 cites W2098123343 @default.
- W1988603902 cites W2148510193 @default.
- W1988603902 cites W2155739760 @default.
- W1988603902 cites W2162248441 @default.
- W1988603902 doi "https://doi.org/10.1016/s0378-4274(03)00175-9" @default.
- W1988603902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12849687" @default.
- W1988603902 hasPublicationYear "2003" @default.
- W1988603902 type Work @default.
- W1988603902 sameAs 1988603902 @default.
- W1988603902 citedByCount "18" @default.
- W1988603902 countsByYear W19886039022013 @default.
- W1988603902 countsByYear W19886039022015 @default.
- W1988603902 countsByYear W19886039022016 @default.
- W1988603902 countsByYear W19886039022018 @default.
- W1988603902 countsByYear W19886039022019 @default.
- W1988603902 countsByYear W19886039022020 @default.
- W1988603902 countsByYear W19886039022021 @default.
- W1988603902 countsByYear W19886039022022 @default.
- W1988603902 countsByYear W19886039022023 @default.
- W1988603902 crossrefType "journal-article" @default.
- W1988603902 hasAuthorship W1988603902A5007381377 @default.
- W1988603902 hasAuthorship W1988603902A5016393150 @default.
- W1988603902 hasAuthorship W1988603902A5021339696 @default.
- W1988603902 hasAuthorship W1988603902A5030161631 @default.
- W1988603902 hasAuthorship W1988603902A5038103250 @default.
- W1988603902 hasAuthorship W1988603902A5041204580 @default.
- W1988603902 hasAuthorship W1988603902A5059583393 @default.
- W1988603902 hasConcept C112672928 @default.
- W1988603902 hasConcept C126322002 @default.
- W1988603902 hasConcept C134018914 @default.
- W1988603902 hasConcept C142773365 @default.
- W1988603902 hasConcept C16685009 @default.
- W1988603902 hasConcept C1998276 @default.
- W1988603902 hasConcept C2778324911 @default.
- W1988603902 hasConcept C2779234561 @default.
- W1988603902 hasConcept C54355233 @default.
- W1988603902 hasConcept C71924100 @default.
- W1988603902 hasConcept C86803240 @default.
- W1988603902 hasConceptScore W1988603902C112672928 @default.
- W1988603902 hasConceptScore W1988603902C126322002 @default.
- W1988603902 hasConceptScore W1988603902C134018914 @default.
- W1988603902 hasConceptScore W1988603902C142773365 @default.
- W1988603902 hasConceptScore W1988603902C16685009 @default.
- W1988603902 hasConceptScore W1988603902C1998276 @default.
- W1988603902 hasConceptScore W1988603902C2778324911 @default.
- W1988603902 hasConceptScore W1988603902C2779234561 @default.
- W1988603902 hasConceptScore W1988603902C54355233 @default.
- W1988603902 hasConceptScore W1988603902C71924100 @default.
- W1988603902 hasConceptScore W1988603902C86803240 @default.
- W1988603902 hasFunder F4320320912 @default.
- W1988603902 hasIssue "3" @default.
- W1988603902 hasLocation W19886039021 @default.
- W1988603902 hasLocation W19886039022 @default.
- W1988603902 hasOpenAccess W1988603902 @default.
- W1988603902 hasPrimaryLocation W19886039021 @default.
- W1988603902 hasRelatedWork W1591616590 @default.
- W1988603902 hasRelatedWork W2000124881 @default.
- W1988603902 hasRelatedWork W2009428258 @default.
- W1988603902 hasRelatedWork W2013275608 @default.
- W1988603902 hasRelatedWork W2036659686 @default.
- W1988603902 hasRelatedWork W2057217014 @default.
- W1988603902 hasRelatedWork W2064652474 @default.
- W1988603902 hasRelatedWork W2101390122 @default.
- W1988603902 hasRelatedWork W2110681150 @default.
- W1988603902 hasRelatedWork W3160140598 @default.
- W1988603902 hasVolume "143" @default.
- W1988603902 isParatext "false" @default.
- W1988603902 isRetracted "false" @default.
- W1988603902 magId "1988603902" @default.
- W1988603902 workType "article" @default.