Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988615302> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1988615302 endingPage "1956" @default.
- W1988615302 startingPage "1948" @default.
- W1988615302 abstract "Abstract Motivation: Query-based biclustering techniques allow interrogating a gene expression compendium with a given gene or gene list. They do so by searching for genes in the compendium that have a profile close to the average expression profile of the genes in this query-list. As it can often not be guaranteed that the genes in a long query-list will all be mutually coexpressed, it is advisable to use each gene separately as a query. This approach, however, leaves the user with a tedious post-processing of partially redundant biclustering results. The fact that for each query-gene multiple parameter settings need to be tested in order to detect the ‘most optimal bicluster size’ adds to the redundancy problem. Results: To aid with this post-processing, we developed an ensemble approach to be used in combination with query-based biclustering. The method relies on a specifically designed consensus matrix in which the biclustering outcomes for multiple query-genes and for different possible parameter settings are merged in a statistically robust way. Clustering of this matrix results in distinct, non-redundant consensus biclusters that maximally reflect the information contained within the original query-based biclustering results. The usefulness of the developed approach is illustrated on a biological case study in Escherichia coli. Availability and implementation: Compiled Matlab code is available from http://homes.esat.kuleuven.be/~kmarchal/Supplementary_Information_DeSmet_2011/. Contact: kathleen.marchal@biw.kuleuven.be Supplementary information:Supplementary data are available at Bioinformatics online." @default.
- W1988615302 created "2016-06-24" @default.
- W1988615302 creator A5037761317 @default.
- W1988615302 creator A5044805939 @default.
- W1988615302 date "2011-05-18" @default.
- W1988615302 modified "2023-10-02" @default.
- W1988615302 title "An ensemble biclustering approach for querying gene expression compendia with experimental lists" @default.
- W1988615302 cites W10762142 @default.
- W1988615302 cites W1548779692 @default.
- W1988615302 cites W1753000577 @default.
- W1988615302 cites W1788633327 @default.
- W1988615302 cites W1983345514 @default.
- W1988615302 cites W2038793346 @default.
- W1988615302 cites W2053906518 @default.
- W1988615302 cites W2060705109 @default.
- W1988615302 cites W2065269753 @default.
- W1988615302 cites W2087503372 @default.
- W1988615302 cites W2098140104 @default.
- W1988615302 cites W2098864059 @default.
- W1988615302 cites W2102147393 @default.
- W1988615302 cites W2112464428 @default.
- W1988615302 cites W2113292893 @default.
- W1988615302 cites W2117379303 @default.
- W1988615302 cites W2118572979 @default.
- W1988615302 cites W2127057035 @default.
- W1988615302 cites W2135098204 @default.
- W1988615302 cites W2136107412 @default.
- W1988615302 cites W2143274936 @default.
- W1988615302 cites W2151936673 @default.
- W1988615302 cites W2154354945 @default.
- W1988615302 cites W2158128075 @default.
- W1988615302 cites W2162532200 @default.
- W1988615302 cites W2163265140 @default.
- W1988615302 cites W2165232124 @default.
- W1988615302 doi "https://doi.org/10.1093/bioinformatics/btr307" @default.
- W1988615302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21593133" @default.
- W1988615302 hasPublicationYear "2011" @default.
- W1988615302 type Work @default.
- W1988615302 sameAs 1988615302 @default.
- W1988615302 citedByCount "9" @default.
- W1988615302 countsByYear W19886153022012 @default.
- W1988615302 countsByYear W19886153022013 @default.
- W1988615302 countsByYear W19886153022015 @default.
- W1988615302 countsByYear W19886153022016 @default.
- W1988615302 countsByYear W19886153022017 @default.
- W1988615302 countsByYear W19886153022018 @default.
- W1988615302 countsByYear W19886153022022 @default.
- W1988615302 countsByYear W19886153022023 @default.
- W1988615302 crossrefType "journal-article" @default.
- W1988615302 hasAuthorship W1988615302A5037761317 @default.
- W1988615302 hasAuthorship W1988615302A5044805939 @default.
- W1988615302 hasBestOaLocation W19886153021 @default.
- W1988615302 hasConcept C124101348 @default.
- W1988615302 hasConcept C144817290 @default.
- W1988615302 hasConcept C154945302 @default.
- W1988615302 hasConcept C166957645 @default.
- W1988615302 hasConcept C23123220 @default.
- W1988615302 hasConcept C2778473407 @default.
- W1988615302 hasConcept C33704608 @default.
- W1988615302 hasConcept C41008148 @default.
- W1988615302 hasConcept C73555534 @default.
- W1988615302 hasConcept C94641424 @default.
- W1988615302 hasConcept C95457728 @default.
- W1988615302 hasConceptScore W1988615302C124101348 @default.
- W1988615302 hasConceptScore W1988615302C144817290 @default.
- W1988615302 hasConceptScore W1988615302C154945302 @default.
- W1988615302 hasConceptScore W1988615302C166957645 @default.
- W1988615302 hasConceptScore W1988615302C23123220 @default.
- W1988615302 hasConceptScore W1988615302C2778473407 @default.
- W1988615302 hasConceptScore W1988615302C33704608 @default.
- W1988615302 hasConceptScore W1988615302C41008148 @default.
- W1988615302 hasConceptScore W1988615302C73555534 @default.
- W1988615302 hasConceptScore W1988615302C94641424 @default.
- W1988615302 hasConceptScore W1988615302C95457728 @default.
- W1988615302 hasIssue "14" @default.
- W1988615302 hasLocation W19886153021 @default.
- W1988615302 hasLocation W19886153022 @default.
- W1988615302 hasOpenAccess W1988615302 @default.
- W1988615302 hasPrimaryLocation W19886153021 @default.
- W1988615302 hasRelatedWork W130049452 @default.
- W1988615302 hasRelatedWork W1967730981 @default.
- W1988615302 hasRelatedWork W2089828626 @default.
- W1988615302 hasRelatedWork W2117814880 @default.
- W1988615302 hasRelatedWork W2124872524 @default.
- W1988615302 hasRelatedWork W2320392928 @default.
- W1988615302 hasRelatedWork W3024886233 @default.
- W1988615302 hasRelatedWork W3197105638 @default.
- W1988615302 hasRelatedWork W763592627 @default.
- W1988615302 hasRelatedWork W2566341957 @default.
- W1988615302 hasVolume "27" @default.
- W1988615302 isParatext "false" @default.
- W1988615302 isRetracted "false" @default.
- W1988615302 magId "1988615302" @default.
- W1988615302 workType "article" @default.