FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988662887> ?p ?o ?g. }

• W1988662887 endingPage "4315" @default.
• W1988662887 startingPage "4311" @default.
• W1988662887 abstract "Primary aromatic amides were prepared by a palladium-catalyzed aminocarbonylation reaction of aryl halides in high yields (70-90%) using formamide as the amine source. The reactions require a palladium catalyst in combination with a nucleophilic Lewis base such as imidazole or 4-(dimethylamino)pyridine (DMAP). Aryl, heteroaryl, and vinyl bromides and chlorides were converted to the primary amides under mild conditions (5 bar, 120 degrees C) using 1 mol % of a palladium-phosphine complex. Best results were obtained in dioxane using triphenylphosphine as the ligand and DMAP as the base. For activated aryl bromides, a phosphine-to-palladium ratio of 2:1 was sufficient, but less reactive aryl bromides or aryl chlorides required ligand-to-palladium ratios up to 8:1 in order to stabilize the catalyst and achieve full conversion. The influence of catalyst, base, solvent, pressure, and temperature was studied in detail. The mechanism of the reaction could be clarified by isolating and identifying the reaction intermediates. In addition, methylamides and dimethylamides were prepared by the same method using N-methylformamide and N,N-dimethylformamide as the amine source." @default.
• W1988662887 created "2016-06-24" @default.
• W1988662887 creator A5001786130 @default.
• W1988662887 creator A5005182277 @default.
• W1988662887 creator A5006450809 @default.
• W1988662887 creator A5024003842 @default.
• W1988662887 creator A5071266313 @default.
• W1988662887 creator A5081901733 @default.
• W1988662887 date "2001-05-12" @default.
• W1988662887 modified "2023-10-16" @default.
• W1988662887 title "Synthesis of Primary Aromatic Amides by Aminocarbonylation of Aryl Halides Using Formamide as an Ammonia Synthon" @default.
• W1988662887 cites W1968606684 @default.
• W1988662887 cites W1995115336 @default.
• W1988662887 cites W2002392171 @default.
• W1988662887 cites W2006172404 @default.
• W1988662887 cites W2023578374 @default.
• W1988662887 cites W2037479280 @default.
• W1988662887 cites W2046070830 @default.
• W1988662887 cites W2089336861 @default.
• W1988662887 cites W2095447777 @default.
• W1988662887 cites W2123052629 @default.
• W1988662887 cites W2951094821 @default.
• W1988662887 cites W2951403859 @default.
• W1988662887 cites W2951422287 @default.
• W1988662887 cites W2951839938 @default.
• W1988662887 cites W2952505148 @default.
• W1988662887 cites W2952867256 @default.
• W1988662887 cites W4247574446 @default.
• W1988662887 cites W4251148645 @default.
• W1988662887 doi "https://doi.org/10.1021/jo015577t" @default.
• W1988662887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11397169" @default.
• W1988662887 hasPublicationYear "2001" @default.
• W1988662887 type Work @default.
• W1988662887 sameAs 1988662887 @default.
• W1988662887 citedByCount "111" @default.
• W1988662887 countsByYear W19886628872012 @default.
• W1988662887 countsByYear W19886628872013 @default.
• W1988662887 countsByYear W19886628872014 @default.
• W1988662887 countsByYear W19886628872015 @default.
• W1988662887 countsByYear W19886628872016 @default.
• W1988662887 countsByYear W19886628872017 @default.
• W1988662887 countsByYear W19886628872018 @default.
• W1988662887 countsByYear W19886628872019 @default.
• W1988662887 countsByYear W19886628872020 @default.
• W1988662887 countsByYear W19886628872021 @default.
• W1988662887 countsByYear W19886628872022 @default.
• W1988662887 countsByYear W19886628872023 @default.
• W1988662887 crossrefType "journal-article" @default.
• W1988662887 hasAuthorship W1988662887A5001786130 @default.
• W1988662887 hasAuthorship W1988662887A5005182277 @default.
• W1988662887 hasAuthorship W1988662887A5006450809 @default.
• W1988662887 hasAuthorship W1988662887A5024003842 @default.
• W1988662887 hasAuthorship W1988662887A5071266313 @default.
• W1988662887 hasAuthorship W1988662887A5081901733 @default.
• W1988662887 hasConcept C116569031 @default.
• W1988662887 hasConcept C155647269 @default.
• W1988662887 hasConcept C161790260 @default.
• W1988662887 hasConcept C168382676 @default.
• W1988662887 hasConcept C170493617 @default.
• W1988662887 hasConcept C178790620 @default.
• W1988662887 hasConcept C178907741 @default.
• W1988662887 hasConcept C185592680 @default.
• W1988662887 hasConcept C2776241998 @default.
• W1988662887 hasConcept C2777247709 @default.
• W1988662887 hasConcept C2777716191 @default.
• W1988662887 hasConcept C2778270854 @default.
• W1988662887 hasConcept C2779485729 @default.
• W1988662887 hasConcept C2780263894 @default.
• W1988662887 hasConcept C2781076698 @default.
• W1988662887 hasConcept C502130503 @default.
• W1988662887 hasConcept C512735826 @default.
• W1988662887 hasConcept C55493867 @default.
• W1988662887 hasConceptScore W1988662887C116569031 @default.
• W1988662887 hasConceptScore W1988662887C155647269 @default.
• W1988662887 hasConceptScore W1988662887C161790260 @default.
• W1988662887 hasConceptScore W1988662887C168382676 @default.
• W1988662887 hasConceptScore W1988662887C170493617 @default.
• W1988662887 hasConceptScore W1988662887C178790620 @default.
• W1988662887 hasConceptScore W1988662887C178907741 @default.
• W1988662887 hasConceptScore W1988662887C185592680 @default.
• W1988662887 hasConceptScore W1988662887C2776241998 @default.
• W1988662887 hasConceptScore W1988662887C2777247709 @default.
• W1988662887 hasConceptScore W1988662887C2777716191 @default.
• W1988662887 hasConceptScore W1988662887C2778270854 @default.
• W1988662887 hasConceptScore W1988662887C2779485729 @default.
• W1988662887 hasConceptScore W1988662887C2780263894 @default.
• W1988662887 hasConceptScore W1988662887C2781076698 @default.
• W1988662887 hasConceptScore W1988662887C502130503 @default.
• W1988662887 hasConceptScore W1988662887C512735826 @default.
• W1988662887 hasConceptScore W1988662887C55493867 @default.
• W1988662887 hasIssue "12" @default.
• W1988662887 hasLocation W19886628871 @default.
• W1988662887 hasLocation W19886628872 @default.
• W1988662887 hasOpenAccess W1988662887 @default.
• W1988662887 hasPrimaryLocation W19886628871 @default.
• W1988662887 hasRelatedWork W1542180417 @default.
• W1988662887 hasRelatedWork W1985768050 @default.
• W1988662887 hasRelatedWork W2024208184 @default.

• next