Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988668619> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W1988668619 endingPage "244" @default.
- W1988668619 startingPage "239" @default.
- W1988668619 abstract "Sustained depolarization of cell membranes and cellular edema are known to accompany various forms of circulatory shock and probably contribute to hypovolemia and cellular dysfunction. It has been proposed that a circulating protein is responsible for these effects. In the present study we have confirmed the existence of a circulating depolarizing factor (CDF) in hemorrhagic shock, burn shock, sepsis, and cardiopulmonary bypass. Plasma samples from pigs or sheep in shock were quantitatively assayed for depolarizing activity using a microelectrode method on rat diaphragm in vitro. The depolarizing effect of CDF in vitro was similar in magnitude to that of shock in situ. We conclude that CDF can entirely account for membrane depolarization during shock. The depolarizing effect of CDF was dose-dependent and saturable; it could be reversed by rinsing the diaphragm with Ringer's or control plasma. CDF activity was detectable in plasma within 5 min after a severe scald and gradually increased over the next 25 min. Resuscitation of hemorrhaged pigs, but not burned sheep, eliminated plasma CDF activity." @default.
- W1988668619 created "2016-06-24" @default.
- W1988668619 creator A5041357207 @default.
- W1988668619 creator A5051776064 @default.
- W1988668619 creator A5054232363 @default.
- W1988668619 creator A5072358602 @default.
- W1988668619 creator A5080042307 @default.
- W1988668619 creator A5084083870 @default.
- W1988668619 date "2001-03-01" @default.
- W1988668619 modified "2023-09-23" @default.
- W1988668619 title "QUANTITATIVE ASSESSMENT OF A CIRCULATING DEPOLARIZING FACTOR IN SHOCK" @default.
- W1988668619 doi "https://doi.org/10.1097/00024382-200115030-00013" @default.
- W1988668619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11236909" @default.
- W1988668619 hasPublicationYear "2001" @default.
- W1988668619 type Work @default.
- W1988668619 sameAs 1988668619 @default.
- W1988668619 citedByCount "20" @default.
- W1988668619 countsByYear W19886686192012 @default.
- W1988668619 countsByYear W19886686192015 @default.
- W1988668619 countsByYear W19886686192016 @default.
- W1988668619 countsByYear W19886686192017 @default.
- W1988668619 countsByYear W19886686192018 @default.
- W1988668619 countsByYear W19886686192019 @default.
- W1988668619 countsByYear W19886686192020 @default.
- W1988668619 countsByYear W19886686192022 @default.
- W1988668619 countsByYear W19886686192023 @default.
- W1988668619 crossrefType "journal-article" @default.
- W1988668619 hasAuthorship W1988668619A5041357207 @default.
- W1988668619 hasAuthorship W1988668619A5051776064 @default.
- W1988668619 hasAuthorship W1988668619A5054232363 @default.
- W1988668619 hasAuthorship W1988668619A5072358602 @default.
- W1988668619 hasAuthorship W1988668619A5080042307 @default.
- W1988668619 hasAuthorship W1988668619A5084083870 @default.
- W1988668619 hasConcept C121332964 @default.
- W1988668619 hasConcept C126322002 @default.
- W1988668619 hasConcept C157138929 @default.
- W1988668619 hasConcept C164292776 @default.
- W1988668619 hasConcept C185592680 @default.
- W1988668619 hasConcept C24890656 @default.
- W1988668619 hasConcept C2781300812 @default.
- W1988668619 hasConcept C2781309813 @default.
- W1988668619 hasConcept C4141045 @default.
- W1988668619 hasConcept C42219234 @default.
- W1988668619 hasConcept C71924100 @default.
- W1988668619 hasConceptScore W1988668619C121332964 @default.
- W1988668619 hasConceptScore W1988668619C126322002 @default.
- W1988668619 hasConceptScore W1988668619C157138929 @default.
- W1988668619 hasConceptScore W1988668619C164292776 @default.
- W1988668619 hasConceptScore W1988668619C185592680 @default.
- W1988668619 hasConceptScore W1988668619C24890656 @default.
- W1988668619 hasConceptScore W1988668619C2781300812 @default.
- W1988668619 hasConceptScore W1988668619C2781309813 @default.
- W1988668619 hasConceptScore W1988668619C4141045 @default.
- W1988668619 hasConceptScore W1988668619C42219234 @default.
- W1988668619 hasConceptScore W1988668619C71924100 @default.
- W1988668619 hasIssue "3" @default.
- W1988668619 hasLocation W19886686191 @default.
- W1988668619 hasLocation W19886686192 @default.
- W1988668619 hasOpenAccess W1988668619 @default.
- W1988668619 hasPrimaryLocation W19886686191 @default.
- W1988668619 hasRelatedWork W1972625762 @default.
- W1988668619 hasRelatedWork W1982221443 @default.
- W1988668619 hasRelatedWork W1988668619 @default.
- W1988668619 hasRelatedWork W2051550641 @default.
- W1988668619 hasRelatedWork W2338545812 @default.
- W1988668619 hasRelatedWork W2417159899 @default.
- W1988668619 hasRelatedWork W2748952813 @default.
- W1988668619 hasRelatedWork W2899084033 @default.
- W1988668619 hasRelatedWork W4237127849 @default.
- W1988668619 hasRelatedWork W4249603230 @default.
- W1988668619 hasVolume "15" @default.
- W1988668619 isParatext "false" @default.
- W1988668619 isRetracted "false" @default.
- W1988668619 magId "1988668619" @default.
- W1988668619 workType "article" @default.