FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988683887> ?p ?o ?g. }

• W1988683887 endingPage "158" @default.
• W1988683887 startingPage "153" @default.
• W1988683887 abstract "Over the last years regulatory T cells (Tregs) were defined as CD4(+)CD25(+) T lymphocytes expressing the transcription factor Foxp3 (Forkhead Box P3) with the ability to downregulate various immune responses. In swine the existence of CD4(+)CD25(+) T lymphocytes was described before but nothing is known about the function of this minor cell population to date. Therefore, we studied porcine CD4(+)CD25(+) T cells with regard to major attributes of murine and human Tregs: their phenotype concerning the expression of several T-cell specific antigens, including Foxp3, their IL-10 production and their suppressive capacity. Our results revealed that porcine CD4(+)CD25(+) T cells with high CD25 expression count for about 2-9% of the CD4(+) T-cell subset. They demonstrate a strong Foxp3 expression, a heterogeneous CD45RC-, CD8alpha- and MHC-II-defined phenotype and a moderate IL-10 production. Co-cultivation of increasing numbers of CD4(+)CD25(high) T cells with a constant number of CD4(+)CD25(-) responder-T cells caused a decrease in proliferation of the entire culture. This demonstrates the suppressive capacity of the CD4(+)CD25(high) T-cell subset and - together with their Foxp3 expression - the existence of porcine Tregs." @default.
• W1988683887 created "2016-06-24" @default.
• W1988683887 creator A5029719511 @default.
• W1988683887 creator A5080826810 @default.
• W1988683887 creator A5082660964 @default.
• W1988683887 creator A5084130326 @default.
• W1988683887 creator A5085332912 @default.
• W1988683887 date "2008-03-01" @default.
• W1988683887 modified "2023-09-24" @default.
• W1988683887 title "Phenotypic and functional characterisation of porcine CD4+CD25high regulatory T cells" @default.
• W1988683887 cites W1526621387 @default.
• W1988683887 cites W1569350768 @default.
• W1988683887 cites W1625897096 @default.
• W1988683887 cites W1986243068 @default.
• W1988683887 cites W2002726823 @default.
• W1988683887 cites W2007978997 @default.
• W1988683887 cites W2019060341 @default.
• W1988683887 cites W2027925603 @default.
• W1988683887 cites W2032311934 @default.
• W1988683887 cites W2034528863 @default.
• W1988683887 cites W2039683692 @default.
• W1988683887 cites W2043310582 @default.
• W1988683887 cites W2052557887 @default.
• W1988683887 cites W2073871743 @default.
• W1988683887 cites W2101230909 @default.
• W1988683887 cites W2114866206 @default.
• W1988683887 cites W2116015828 @default.
• W1988683887 cites W2127755180 @default.
• W1988683887 cites W2128940814 @default.
• W1988683887 cites W2136245823 @default.
• W1988683887 cites W2158423857 @default.
• W1988683887 cites W4313324526 @default.
• W1988683887 doi "https://doi.org/10.1016/j.vetimm.2007.08.002" @default.
• W1988683887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17868905" @default.
• W1988683887 hasPublicationYear "2008" @default.
• W1988683887 type Work @default.
• W1988683887 sameAs 1988683887 @default.
• W1988683887 citedByCount "78" @default.
• W1988683887 countsByYear W19886838872012 @default.
• W1988683887 countsByYear W19886838872013 @default.
• W1988683887 countsByYear W19886838872014 @default.
• W1988683887 countsByYear W19886838872015 @default.
• W1988683887 countsByYear W19886838872016 @default.
• W1988683887 countsByYear W19886838872017 @default.
• W1988683887 countsByYear W19886838872018 @default.
• W1988683887 countsByYear W19886838872019 @default.
• W1988683887 countsByYear W19886838872020 @default.
• W1988683887 countsByYear W19886838872021 @default.
• W1988683887 countsByYear W19886838872022 @default.
• W1988683887 countsByYear W19886838872023 @default.
• W1988683887 crossrefType "journal-article" @default.
• W1988683887 hasAuthorship W1988683887A5029719511 @default.
• W1988683887 hasAuthorship W1988683887A5080826810 @default.
• W1988683887 hasAuthorship W1988683887A5082660964 @default.
• W1988683887 hasAuthorship W1988683887A5084130326 @default.
• W1988683887 hasAuthorship W1988683887A5085332912 @default.
• W1988683887 hasConcept C104317684 @default.
• W1988683887 hasConcept C127716648 @default.
• W1988683887 hasConcept C153911025 @default.
• W1988683887 hasConcept C203014093 @default.
• W1988683887 hasConcept C2776090121 @default.
• W1988683887 hasConcept C2779727006 @default.
• W1988683887 hasConcept C2908647359 @default.
• W1988683887 hasConcept C54355233 @default.
• W1988683887 hasConcept C71924100 @default.
• W1988683887 hasConcept C79484868 @default.
• W1988683887 hasConcept C86803240 @default.
• W1988683887 hasConcept C8891405 @default.
• W1988683887 hasConcept C95444343 @default.
• W1988683887 hasConcept C99454951 @default.
• W1988683887 hasConceptScore W1988683887C104317684 @default.
• W1988683887 hasConceptScore W1988683887C127716648 @default.
• W1988683887 hasConceptScore W1988683887C153911025 @default.
• W1988683887 hasConceptScore W1988683887C203014093 @default.
• W1988683887 hasConceptScore W1988683887C2776090121 @default.
• W1988683887 hasConceptScore W1988683887C2779727006 @default.
• W1988683887 hasConceptScore W1988683887C2908647359 @default.
• W1988683887 hasConceptScore W1988683887C54355233 @default.
• W1988683887 hasConceptScore W1988683887C71924100 @default.
• W1988683887 hasConceptScore W1988683887C79484868 @default.
• W1988683887 hasConceptScore W1988683887C86803240 @default.
• W1988683887 hasConceptScore W1988683887C8891405 @default.
• W1988683887 hasConceptScore W1988683887C95444343 @default.
• W1988683887 hasConceptScore W1988683887C99454951 @default.
• W1988683887 hasIssue "1-2" @default.
• W1988683887 hasLocation W19886838871 @default.
• W1988683887 hasLocation W19886838872 @default.
• W1988683887 hasOpenAccess W1988683887 @default.
• W1988683887 hasPrimaryLocation W19886838871 @default.
• W1988683887 hasRelatedWork W130785812 @default.
• W1988683887 hasRelatedWork W1507822347 @default.
• W1988683887 hasRelatedWork W1754949563 @default.
• W1988683887 hasRelatedWork W1992037894 @default.
• W1988683887 hasRelatedWork W2059748759 @default.
• W1988683887 hasRelatedWork W2119314438 @default.
• W1988683887 hasRelatedWork W2382901196 @default.
• W1988683887 hasRelatedWork W2474300931 @default.
• W1988683887 hasRelatedWork W2890210959 @default.

• next