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- W1988685771 abstract "Intraperitoneal administration of ketamine produced dose-dependent hypothermia at the ambient temperatures (T a ) of both 8 and 23 °C in unanesthetized rats. At a T a of 8 °C, the hypothermia was brought about solely by a decrease in metabolic heat production. There were no changes in either the tail skin temperature (T tail ) or the sole skin temperature (T sole ). At a T a of 23 °C, the hypothermia was due to an increase in T tail , an increase in T sole , and a decrease in metabolic heat production. However, at a T a of 31 °C, there were no changes in rectal temperature in response to ketamine application, since neither heat production nor skin temperatures (e.g., T tail and T sole ) was affected by ketamine at this T a . The data indicate that the effect of the drug treatment may be to decrease heat production and (or) increase heat loss." @default.
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- W1988685771 date "1978-12-01" @default.
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- W1988685771 title "Effect of ketamine on thermoregulation in rats" @default.
- W1988685771 doi "https://doi.org/10.1139/y78-153" @default.
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