FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988691569> ?p ?o ?g. }

• W1988691569 endingPage "423" @default.
• W1988691569 startingPage "415" @default.
• W1988691569 abstract "Atherosclerosis is a chronic inflammatory process involving the activity of several cytokines and growth factors. Platelet-derived growth factor-A (PDGF-A) and PDGF-B are important mitogens and chemoattractants for monocytes as well as smooth muscle cells. We sought to identify the role of PDGF-C and PDGF-D, two new members of the PDGF family, in monocyte migration and differentiation. We also assessed their effects in regulating matrix metalloproteinase-2 (MMP-2) and MMP-9, which are important for cell migration.PDGF-C and PDGF-D were expressed in macrophages, smooth muscle cells, and endothelial cells in human atherosclerotic plaques, as shown by immunohistochemical analysis. PDGF-C and PDGF-D mRNA and protein expression was induced after differentiation of THP-1 monocytes to macrophages, and both PDGF-C and PDGF-D induced MMP-9 mRNA expression in a concentration-dependent manner. Treatment of cells with PDGF-C or PDGF-D enhanced the secretion of MMP-2 and MMP-9 in a cell-dependent manner. In a migration assay using a Boyden chamber with 8 microm pore size, PDGF-C and PDGF-D attracted THP-1 monocytes in a concentration-dependent manner.Our data suggest that PDGF-C and PDGF-D, like PDGF-A and PDGF-B, play important roles in atherosclerosis by stimulating MMP activity and influencing monocyte migration." @default.
• W1988691569 created "2016-06-24" @default.
• W1988691569 creator A5004241415 @default.
• W1988691569 creator A5020206391 @default.
• W1988691569 creator A5043556773 @default.
• W1988691569 creator A5086883564 @default.
• W1988691569 date "2009-02-01" @default.
• W1988691569 modified "2023-10-10" @default.
• W1988691569 title "Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression" @default.
• W1988691569 cites W1673643619 @default.
• W1988691569 cites W1957628343 @default.
• W1988691569 cites W1969552991 @default.
• W1988691569 cites W1970387504 @default.
• W1988691569 cites W1974790290 @default.
• W1988691569 cites W2001881013 @default.
• W1988691569 cites W2017281751 @default.
• W1988691569 cites W2030728462 @default.
• W1988691569 cites W2034955326 @default.
• W1988691569 cites W2035599975 @default.
• W1988691569 cites W2038115763 @default.
• W1988691569 cites W2053806341 @default.
• W1988691569 cites W2058917890 @default.
• W1988691569 cites W2063650204 @default.
• W1988691569 cites W2065041063 @default.
• W1988691569 cites W2066963386 @default.
• W1988691569 cites W2090128598 @default.
• W1988691569 cites W2094941678 @default.
• W1988691569 cites W2101409569 @default.
• W1988691569 cites W2108050139 @default.
• W1988691569 cites W2113902557 @default.
• W1988691569 cites W2121019995 @default.
• W1988691569 cites W2122150183 @default.
• W1988691569 cites W2128614663 @default.
• W1988691569 cites W2129107628 @default.
• W1988691569 cites W2144075923 @default.
• W1988691569 cites W2159232436 @default.
• W1988691569 cites W2165209993 @default.
• W1988691569 cites W2170882418 @default.
• W1988691569 doi "https://doi.org/10.1016/j.atherosclerosis.2008.04.050" @default.
• W1988691569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18573494" @default.
• W1988691569 hasPublicationYear "2009" @default.
• W1988691569 type Work @default.
• W1988691569 sameAs 1988691569 @default.
• W1988691569 citedByCount "72" @default.
• W1988691569 countsByYear W19886915692012 @default.
• W1988691569 countsByYear W19886915692013 @default.
• W1988691569 countsByYear W19886915692014 @default.
• W1988691569 countsByYear W19886915692015 @default.
• W1988691569 countsByYear W19886915692016 @default.
• W1988691569 countsByYear W19886915692017 @default.
• W1988691569 countsByYear W19886915692018 @default.
• W1988691569 countsByYear W19886915692020 @default.
• W1988691569 countsByYear W19886915692021 @default.
• W1988691569 countsByYear W19886915692022 @default.
• W1988691569 countsByYear W19886915692023 @default.
• W1988691569 crossrefType "journal-article" @default.
• W1988691569 hasAuthorship W1988691569A5004241415 @default.
• W1988691569 hasAuthorship W1988691569A5020206391 @default.
• W1988691569 hasAuthorship W1988691569A5043556773 @default.
• W1988691569 hasAuthorship W1988691569A5086883564 @default.
• W1988691569 hasConcept C109523444 @default.
• W1988691569 hasConcept C170493617 @default.
• W1988691569 hasConcept C180361614 @default.
• W1988691569 hasConcept C185592680 @default.
• W1988691569 hasConcept C203014093 @default.
• W1988691569 hasConcept C2775960820 @default.
• W1988691569 hasConcept C2781184567 @default.
• W1988691569 hasConcept C2781294074 @default.
• W1988691569 hasConcept C55493867 @default.
• W1988691569 hasConcept C86803240 @default.
• W1988691569 hasConcept C95444343 @default.
• W1988691569 hasConceptScore W1988691569C109523444 @default.
• W1988691569 hasConceptScore W1988691569C170493617 @default.
• W1988691569 hasConceptScore W1988691569C180361614 @default.
• W1988691569 hasConceptScore W1988691569C185592680 @default.
• W1988691569 hasConceptScore W1988691569C203014093 @default.
• W1988691569 hasConceptScore W1988691569C2775960820 @default.
• W1988691569 hasConceptScore W1988691569C2781184567 @default.
• W1988691569 hasConceptScore W1988691569C2781294074 @default.
• W1988691569 hasConceptScore W1988691569C55493867 @default.
• W1988691569 hasConceptScore W1988691569C86803240 @default.
• W1988691569 hasConceptScore W1988691569C95444343 @default.
• W1988691569 hasIssue "2" @default.
• W1988691569 hasLocation W19886915691 @default.
• W1988691569 hasLocation W19886915692 @default.
• W1988691569 hasOpenAccess W1988691569 @default.
• W1988691569 hasPrimaryLocation W19886915691 @default.
• W1988691569 hasRelatedWork W1988539054 @default.
• W1988691569 hasRelatedWork W1993789860 @default.
• W1988691569 hasRelatedWork W2050268899 @default.
• W1988691569 hasRelatedWork W2078751457 @default.
• W1988691569 hasRelatedWork W2087890016 @default.
• W1988691569 hasRelatedWork W2173917538 @default.
• W1988691569 hasRelatedWork W2431952740 @default.
• W1988691569 hasRelatedWork W368310162 @default.
• W1988691569 hasRelatedWork W4283700508 @default.
• W1988691569 hasRelatedWork W952563013 @default.
• W1988691569 hasVolume "202" @default.

• next