FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988790156> ?p ?o ?g. }

• W1988790156 endingPage "2036" @default.
• W1988790156 startingPage "2029" @default.
• W1988790156 abstract "Immunohistochemistry (IHC) testing for mismatch repair proteins (MMRP) is currently being used primarily in colorectal cancer resection specimens. We aimed to compare the results of IHC staining performed on biopsy specimens obtained at endoscopy with that performed on surgical specimens after neoadjuvant therapy. Thirty-two rectal cancer subjects had paired preneoadjuvant and postneoadjuvant tissue available for IHC staining (MLH1, MSH2, MSH6, and PMS2), whereas 39 rectosigmoid cancer patients who did not receive neoadjuvant treatment served as controls. Each slide received a qualitative (absent, focal, and strong) and quantitative score (immunoreactivity [0-3] × percent positivity [0-4]). The quantitative scores of MMRP from the operative material were significantly lower in the neoadjuvant group than in the control (P < .05 for all).The scores of all MMRP from endoscopic biopsies were not significantly different between the neoadjuvant and the control groups. Disagreement between the endoscopic biopsy and the operative material was evident in 23 of 128 stains (18.5%) in the neoadjuvant group and in 12 of 156 stains (7.7%) in the control group (P = .009). In the neoadjuvant group, a disagreement pattern of endoscopic strong operative focal was observed in 28.1% for PMS2, 12.5% for MSH6, 12.5% for MLH1, and 6.3% for MSH2, and in the control group, this same disagreement pattern was found in 12.8% for PMS2, 7.7% for MSH6, 7.7% for MLH1, and 0% for MSH2. Based on our findings, we suggest that for rectal cancer, the endoscopic material rather than the operative material should serve as the primary material for IHC staining." @default.
• W1988790156 created "2016-06-24" @default.
• W1988790156 creator A5013101484 @default.
• W1988790156 creator A5014548307 @default.
• W1988790156 creator A5017345957 @default.
• W1988790156 creator A5019432358 @default.
• W1988790156 creator A5032518260 @default.
• W1988790156 creator A5036334249 @default.
• W1988790156 creator A5040780841 @default.
• W1988790156 creator A5043544734 @default.
• W1988790156 creator A5053639618 @default.
• W1988790156 creator A5055862445 @default.
• W1988790156 creator A5062440608 @default.
• W1988790156 creator A5076236111 @default.
• W1988790156 date "2014-10-01" @default.
• W1988790156 modified "2023-10-01" @default.
• W1988790156 title "How reliable is immunohistochemical staining for DNA mismatch repair proteins performed after neoadjuvant chemoradiation?" @default.
• W1988790156 cites W1808952474 @default.
• W1988790156 cites W1874768599 @default.
• W1988790156 cites W1967017324 @default.
• W1988790156 cites W1968414715 @default.
• W1988790156 cites W1971116157 @default.
• W1988790156 cites W1990255259 @default.
• W1988790156 cites W1993051520 @default.
• W1988790156 cites W2000310502 @default.
• W1988790156 cites W2012502866 @default.
• W1988790156 cites W2020275763 @default.
• W1988790156 cites W2024346369 @default.
• W1988790156 cites W2032107446 @default.
• W1988790156 cites W2032518516 @default.
• W1988790156 cites W2040879252 @default.
• W1988790156 cites W2041566574 @default.
• W1988790156 cites W2048179657 @default.
• W1988790156 cites W2049751453 @default.
• W1988790156 cites W2062850641 @default.
• W1988790156 cites W2064329151 @default.
• W1988790156 cites W2081993522 @default.
• W1988790156 cites W2087835419 @default.
• W1988790156 cites W2112565258 @default.
• W1988790156 cites W2114874133 @default.
• W1988790156 cites W2131725426 @default.
• W1988790156 cites W2145297551 @default.
• W1988790156 cites W2146652564 @default.
• W1988790156 cites W2147517951 @default.
• W1988790156 cites W2158189974 @default.
• W1988790156 cites W2162362353 @default.
• W1988790156 cites W2163792536 @default.
• W1988790156 cites W2165606389 @default.
• W1988790156 cites W2167233646 @default.
• W1988790156 doi "https://doi.org/10.1016/j.humpath.2014.07.005" @default.
• W1988790156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25150747" @default.
• W1988790156 hasPublicationYear "2014" @default.
• W1988790156 type Work @default.
• W1988790156 sameAs 1988790156 @default.
• W1988790156 citedByCount "31" @default.
• W1988790156 countsByYear W19887901562015 @default.
• W1988790156 countsByYear W19887901562017 @default.
• W1988790156 countsByYear W19887901562018 @default.
• W1988790156 countsByYear W19887901562019 @default.
• W1988790156 countsByYear W19887901562020 @default.
• W1988790156 countsByYear W19887901562022 @default.
• W1988790156 countsByYear W19887901562023 @default.
• W1988790156 crossrefType "journal-article" @default.
• W1988790156 hasAuthorship W1988790156A5013101484 @default.
• W1988790156 hasAuthorship W1988790156A5014548307 @default.
• W1988790156 hasAuthorship W1988790156A5017345957 @default.
• W1988790156 hasAuthorship W1988790156A5019432358 @default.
• W1988790156 hasAuthorship W1988790156A5032518260 @default.
• W1988790156 hasAuthorship W1988790156A5036334249 @default.
• W1988790156 hasAuthorship W1988790156A5040780841 @default.
• W1988790156 hasAuthorship W1988790156A5043544734 @default.
• W1988790156 hasAuthorship W1988790156A5053639618 @default.
• W1988790156 hasAuthorship W1988790156A5055862445 @default.
• W1988790156 hasAuthorship W1988790156A5062440608 @default.
• W1988790156 hasAuthorship W1988790156A5076236111 @default.
• W1988790156 hasConcept C111425858 @default.
• W1988790156 hasConcept C121608353 @default.
• W1988790156 hasConcept C126322002 @default.
• W1988790156 hasConcept C142724271 @default.
• W1988790156 hasConcept C143998085 @default.
• W1988790156 hasConcept C204232928 @default.
• W1988790156 hasConcept C2775934546 @default.
• W1988790156 hasConcept C2776559941 @default.
• W1988790156 hasConcept C2776674815 @default.
• W1988790156 hasConcept C2778292576 @default.
• W1988790156 hasConcept C2778677574 @default.
• W1988790156 hasConcept C2779115348 @default.
• W1988790156 hasConcept C526805850 @default.
• W1988790156 hasConcept C530470458 @default.
• W1988790156 hasConcept C60748783 @default.
• W1988790156 hasConcept C71924100 @default.
• W1988790156 hasConceptScore W1988790156C111425858 @default.
• W1988790156 hasConceptScore W1988790156C121608353 @default.
• W1988790156 hasConceptScore W1988790156C126322002 @default.
• W1988790156 hasConceptScore W1988790156C142724271 @default.
• W1988790156 hasConceptScore W1988790156C143998085 @default.
• W1988790156 hasConceptScore W1988790156C204232928 @default.
• W1988790156 hasConceptScore W1988790156C2775934546 @default.

• next