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- W1988807673 abstract "Novel biophysical approaches combined with modeling and new biochemical data have helped to recharge the lipid raft field and have contributed to the generation of a refined model of plasma membrane organization. In this review, we summarize new information in the context of previous literature to provide new insights into the spatial organization and dynamics of lipids and proteins in the plasma membrane of live cells. Recent findings of large-scale separation of liquid-ordered and liquid-disordered phases in plasma membrane vesicles demonstrate this capacity within the complex milieu of plasma membrane proteins and lipids. Roles for membrane heterogeneity and reorganization in immune cell activation are discussed in light of this new information." @default.
- W1988807673 created "2016-06-24" @default.
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- W1988807673 creator A5048526342 @default.
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- W1988807673 date "2007-10-01" @default.
- W1988807673 modified "2023-09-30" @default.
- W1988807673 title "Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function" @default.
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- W1988807673 doi "https://doi.org/10.1016/j.semcdb.2007.07.010" @default.
- W1988807673 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2147712" @default.
- W1988807673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17764993" @default.
- W1988807673 hasPublicationYear "2007" @default.
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