Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988823395> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1988823395 endingPage "367" @default.
- W1988823395 startingPage "361" @default.
- W1988823395 abstract "The human immunodeficiency virus (HIV) is surrounded by a rigid membrane rich in cholesterol. Extraction of cholesterol from the virus envelope reduces its infectivity in vitro. Large amounts of lipid emulsion phospholipids have the property of extracting cholesterol from cell membranes. The purpose of the present study was to observe the effects of high phospholipid loads on the lipid profile as well as HIV infectivity of patients with acquired immunodeficiency syndrome (AIDS). Fifty-nine patients with AIDS, weight loss, and presenting Pneumocystis carinii pneumonia (PCP) were included in a prospective, randomised, controlled study. In addition to standard therapy, patients received for 2 weeks 910 kcal of peripheral parenteral nutrition including 20% lipid emulsion (group 1) or a new 2% lipid emulsion with a high phospholipid/triglyceride ratio (1:1.7) (group 2). Activity level and biological, immune and HIV load and infectivity parameters were followed. Cholesterol increased from 113 ± 44 to 228 ± 103 mg/dl in the 2% group (P < 0.00001). Triglycerides also increased significantly (P < 0.02). IgA was decreased in the 2% group. HIV load and infectivity tests and leukocyte subsets did not demonstrate any effect of the lipid emulsions. It is concluded that the new 2% emulsion is a powerful cholesterol extractor. However, 2 weeks' administration failed to show any efficacy in modifying immune parameters or HIV infectivity in AIDS patients with PCP." @default.
- W1988823395 created "2016-06-24" @default.
- W1988823395 creator A5026652265 @default.
- W1988823395 creator A5081416237 @default.
- W1988823395 creator A5091520008 @default.
- W1988823395 date "1994-12-01" @default.
- W1988823395 modified "2023-09-27" @default.
- W1988823395 title "Short-term effects of lipid-based parenteral nutrition in patients with acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia" @default.
- W1988823395 cites W1500976046 @default.
- W1988823395 cites W1766169539 @default.
- W1988823395 cites W1788936017 @default.
- W1988823395 cites W1921768926 @default.
- W1988823395 cites W1965027028 @default.
- W1988823395 cites W1979173807 @default.
- W1988823395 cites W1991655565 @default.
- W1988823395 cites W1999682728 @default.
- W1988823395 cites W2020712303 @default.
- W1988823395 cites W2022835671 @default.
- W1988823395 cites W2034804230 @default.
- W1988823395 cites W2057444535 @default.
- W1988823395 cites W2068053744 @default.
- W1988823395 cites W2073736643 @default.
- W1988823395 cites W2093962401 @default.
- W1988823395 cites W2094394242 @default.
- W1988823395 cites W2131224322 @default.
- W1988823395 cites W2322541596 @default.
- W1988823395 cites W2473099693 @default.
- W1988823395 cites W279399108 @default.
- W1988823395 cites W68929746 @default.
- W1988823395 cites W2014124494 @default.
- W1988823395 cites W2056338288 @default.
- W1988823395 cites W2622794778 @default.
- W1988823395 doi "https://doi.org/10.1016/0261-5614(94)90026-4" @default.
- W1988823395 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16843415" @default.
- W1988823395 hasPublicationYear "1994" @default.
- W1988823395 type Work @default.
- W1988823395 sameAs 1988823395 @default.
- W1988823395 citedByCount "1" @default.
- W1988823395 crossrefType "journal-article" @default.
- W1988823395 hasAuthorship W1988823395A5026652265 @default.
- W1988823395 hasAuthorship W1988823395A5081416237 @default.
- W1988823395 hasAuthorship W1988823395A5091520008 @default.
- W1988823395 hasConcept C106358424 @default.
- W1988823395 hasConcept C126322002 @default.
- W1988823395 hasConcept C203014093 @default.
- W1988823395 hasConcept C2522874641 @default.
- W1988823395 hasConcept C2777559004 @default.
- W1988823395 hasConcept C2777607303 @default.
- W1988823395 hasConcept C2777914695 @default.
- W1988823395 hasConcept C2778163477 @default.
- W1988823395 hasConcept C2778270857 @default.
- W1988823395 hasConcept C2778918659 @default.
- W1988823395 hasConcept C2993443204 @default.
- W1988823395 hasConcept C41625074 @default.
- W1988823395 hasConcept C55493867 @default.
- W1988823395 hasConcept C71924100 @default.
- W1988823395 hasConcept C86803240 @default.
- W1988823395 hasConcept C8891405 @default.
- W1988823395 hasConcept C90924648 @default.
- W1988823395 hasConceptScore W1988823395C106358424 @default.
- W1988823395 hasConceptScore W1988823395C126322002 @default.
- W1988823395 hasConceptScore W1988823395C203014093 @default.
- W1988823395 hasConceptScore W1988823395C2522874641 @default.
- W1988823395 hasConceptScore W1988823395C2777559004 @default.
- W1988823395 hasConceptScore W1988823395C2777607303 @default.
- W1988823395 hasConceptScore W1988823395C2777914695 @default.
- W1988823395 hasConceptScore W1988823395C2778163477 @default.
- W1988823395 hasConceptScore W1988823395C2778270857 @default.
- W1988823395 hasConceptScore W1988823395C2778918659 @default.
- W1988823395 hasConceptScore W1988823395C2993443204 @default.
- W1988823395 hasConceptScore W1988823395C41625074 @default.
- W1988823395 hasConceptScore W1988823395C55493867 @default.
- W1988823395 hasConceptScore W1988823395C71924100 @default.
- W1988823395 hasConceptScore W1988823395C86803240 @default.
- W1988823395 hasConceptScore W1988823395C8891405 @default.
- W1988823395 hasConceptScore W1988823395C90924648 @default.
- W1988823395 hasIssue "6" @default.
- W1988823395 hasLocation W19888233951 @default.
- W1988823395 hasLocation W19888233952 @default.
- W1988823395 hasOpenAccess W1988823395 @default.
- W1988823395 hasPrimaryLocation W19888233951 @default.
- W1988823395 hasRelatedWork W1506984959 @default.
- W1988823395 hasRelatedWork W188736551 @default.
- W1988823395 hasRelatedWork W1979132127 @default.
- W1988823395 hasRelatedWork W1988823395 @default.
- W1988823395 hasRelatedWork W2023306820 @default.
- W1988823395 hasRelatedWork W2123304061 @default.
- W1988823395 hasRelatedWork W2403917481 @default.
- W1988823395 hasRelatedWork W2412328347 @default.
- W1988823395 hasRelatedWork W4246046073 @default.
- W1988823395 hasRelatedWork W2041773663 @default.
- W1988823395 hasVolume "13" @default.
- W1988823395 isParatext "false" @default.
- W1988823395 isRetracted "false" @default.
- W1988823395 magId "1988823395" @default.
- W1988823395 workType "article" @default.