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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988841006> ?p ?o ?g. }

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• W1988841006 abstract "Protein function prediction is an active area of research in bioinformatics. Yet, the transfer of annotation on the basis of sequence or structural similarity remains widely used as an annotation method. Most of today's machine learning approaches reduce the problem to a collection of binary classification problems: whether a protein performs a particular function, sometimes with a post-processing step to combine the binary outputs. We propose a method that directly predicts a full functional annotation of a protein by modeling the structure of the Gene Ontology hierarchy in the framework of kernel methods for structured-output spaces. Our empirical results show improved performance over a BLAST nearest-neighbor method, and over algorithms that employ a collection of binary classifiers as measured on the Mousefunc benchmark dataset." @default.
• W1988841006 created "2016-06-24" @default.
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• W1988841006 date "2010-04-01" @default.
• W1988841006 modified "2023-10-01" @default.
• W1988841006 title "HIERARCHICAL CLASSIFICATION OF GENE ONTOLOGY TERMS USING THE GOstruct METHOD" @default.
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• W1988841006 doi "https://doi.org/10.1142/s0219720010004744" @default.
• W1988841006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20401950" @default.
• W1988841006 hasPublicationYear "2010" @default.
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