Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988861745> ?p ?o ?g. }
Showing items 1 to 49 of
49
with 100 items per page.
- W1988861745 endingPage "51" @default.
- W1988861745 startingPage "45" @default.
- W1988861745 abstract "Previous studies have shown that the predominant proteins secreted by the seminal vesicles are transglutaminase substrates which have undergone major structural alterations during evolution. In man, they are known as semenogelin I and II; recently it was shown that, similar to man, several new world and old world monkeys carry two semenogelin genes as well, the exception being the cotton-top tamarin (Saguinus oedipus) with a single gene. This gene has now been cloned and identified as a semenogelin I gene, because of a higher number of conserved nucleotides in the human semenogelin I gene (89 %) than in the human and the rhesus monkey semenogelin II genes (82 %). Furthermore, the difference in sequence similarity indicates that the semenogelin II gene was deleted from the genome of a progenitor to the cotton-top tamarin after the duplication that yielded the two semenogelin genes seen in man. Like several other genes expressing seminal-vesicle-secreted transglutaminase substrates, the cotton-top tamarin semenogelin I gene consists of three exons of 97, 1816 and 146 bp. It codes for a signal peptide of 23 amino acid residues and the secreted protein of 592 amino acid residues. The molecular mass of 66 kDa is 32 % larger than that of the human counterpart and, contrary to human semenogelin I, the cotton-top tamarin protein has the potential to be highly glycosylated as there are 14 sites with the consensus sequence for N-linked glycosylation. Approximately half of the primary structure consists of five nearly identical tandem repeats of 58 amino acid residues, that probably evolved relatively late." @default.
- W1988861745 created "2016-06-24" @default.
- W1988861745 creator A5047505231 @default.
- W1988861745 date "1998-07-01" @default.
- W1988861745 modified "2023-10-16" @default.
- W1988861745 title "The cotton-top tamarin carries an extended semenogelin I gene but no semenogelin II gene" @default.
- W1988861745 doi "https://doi.org/10.1046/j.1432-1327.1998.2550045.x" @default.
- W1988861745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9692899" @default.
- W1988861745 hasPublicationYear "1998" @default.
- W1988861745 type Work @default.
- W1988861745 sameAs 1988861745 @default.
- W1988861745 citedByCount "17" @default.
- W1988861745 countsByYear W19888617452017 @default.
- W1988861745 countsByYear W19888617452021 @default.
- W1988861745 crossrefType "journal-article" @default.
- W1988861745 hasAuthorship W1988861745A5047505231 @default.
- W1988861745 hasBestOaLocation W19888617451 @default.
- W1988861745 hasConcept C104317684 @default.
- W1988861745 hasConcept C36823959 @default.
- W1988861745 hasConcept C54355233 @default.
- W1988861745 hasConcept C55493867 @default.
- W1988861745 hasConcept C86803240 @default.
- W1988861745 hasConceptScore W1988861745C104317684 @default.
- W1988861745 hasConceptScore W1988861745C36823959 @default.
- W1988861745 hasConceptScore W1988861745C54355233 @default.
- W1988861745 hasConceptScore W1988861745C55493867 @default.
- W1988861745 hasConceptScore W1988861745C86803240 @default.
- W1988861745 hasIssue "1" @default.
- W1988861745 hasLocation W19888617451 @default.
- W1988861745 hasLocation W19888617452 @default.
- W1988861745 hasOpenAccess W1988861745 @default.
- W1988861745 hasPrimaryLocation W19888617451 @default.
- W1988861745 hasRelatedWork W2025851750 @default.
- W1988861745 hasRelatedWork W2035919360 @default.
- W1988861745 hasRelatedWork W2039352533 @default.
- W1988861745 hasRelatedWork W2059736436 @default.
- W1988861745 hasRelatedWork W2090999728 @default.
- W1988861745 hasRelatedWork W2092554027 @default.
- W1988861745 hasRelatedWork W2168467210 @default.
- W1988861745 hasRelatedWork W2349396032 @default.
- W1988861745 hasRelatedWork W2385130702 @default.
- W1988861745 hasRelatedWork W4242521457 @default.
- W1988861745 hasVolume "255" @default.
- W1988861745 isParatext "false" @default.
- W1988861745 isRetracted "false" @default.
- W1988861745 magId "1988861745" @default.
- W1988861745 workType "article" @default.