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- W1988880811 abstract "The obese gene product, leptin, is synthesized in adipose tissue and is a circulating factor regulating body weight. To identify the location of leptin receptors in the brain we have performed an autoradiographic study of the binding of [(125)I]leptin to frozen sections of mouse brain. Dense specific binding of [(125)I]leptin was found only in the choroid plexus which is located in the dorsal part of the third ventricle and lateral ventricles. Specific binding of [(125)I]leptin was found the ob/ob and db/db mice. These findings further our understanding of the sites and mechanism of action of leptin on brain centers regulating body weight." @default.
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- W1988880811 date "1996-02-01" @default.
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- W1988880811 title "Autoradiographic Localization of Leptin Binding in the Choroid Plexus ofob/obanddb/dbMice" @default.
- W1988880811 doi "https://doi.org/10.1006/bbrc.1996.0328" @default.
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