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• W1988890609 abstract "<b>Aims and objectives:</b> The purpose of this study was to evaluate and compare the anti-inflammatory activity of the aqueous root bark extract of <i>Aegle marmelos</i> (Bilwa) in experimental acute and chronic inflammatory animal models. <br> <b>Materials and Methods:</b> Aqueous extract of root bark of Bilwa was prepared and tested for anti-inflammatory activity in albino rats weighing 150-280 grams. The animals were randomly divided into 3 groups of 6 each; one group served as control and other two groups received indomethacin and Bilwa orally 1 hour prior to experimentation. The <i>in vivo</i> anti-inflammatory activity was studied using the acute (Carrageenan induced paw edema) and chronic (Cotton pellet induced granuloma) animal models. Anti-inflammatory activity was expressed as Percent inhibition (PI). Statistical analysis was performed using One-way analysis of variance (ANOVA) followed by Scheffe's post hoc test. P < 0.05 was considered statistically significant.<br> <b>Results:</b> The PI with indomethacin and Bilwa in carrageenan induced paw edema were 52.7% and 46% and in cotton pellet induced granuloma were 24.7% and 9.2% respectively. Indomethacin showed highly significant anti-inflammatory activity in both the models. However, Bilwa showed highly significant activity in acute model and but a trend of anti-inflammatory activity in chronic model studied. <br><b>Conclusions:</b> As Bilwa showed significant anti-inflammatory activity in the models studied, it can be a promising anti-inflammatory agent." @default.
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• W1988890609 date "2011-01-01" @default.
• W1988890609 modified "2023-10-16" @default.
• W1988890609 title "Evaluation of the anti-inflammatory activity of Aegle marmelos (Bilwa) root" @default.
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• W1988890609 doi "https://doi.org/10.4103/0253-7613.83108" @default.
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