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• W1988948234 abstract "RationaleTo characterize initial allergic reactions to seafood (fish and shellfish) in children.MethodsCharts of children diagnosed with seafood allergy between 1991 and 2011 (based on history and positive skin test /elevated fish-specific IgE) at the Montreal Children's Hospital were reviewed. Subjects with unclear history or resolved allergy were excluded. Data was collected on clinical characteristics of the initial reaction, culprit food, demographics and history of atopy. Reactions involving the gastrointestinal/respiratory/ cardiovascular systems were defined as moderate/severe.ResultsOne hundred and thirty-five fish and 95 shellfish allergic children were identified. Median age at initial reaction was 2.4 years for fish and 8.7 years for shellfish (interquartile range: 1.1, 4.2 and 4.3, 11.7 respectively). Reactions to fish and shellfish were more common in males, 60.3% (95%CI, 51.4%, 68.7%) and 55.8% (95%CI, 45.3%, 65.8%), respectively. Reactions occurred mostly after ingestion (94.7% (95%CI, 88.9%, 97.6%) and 92.6% (95%CI, 84.9%, 96.7%) respectively). The commonest fish and shellfish implicated were salmon (27.4% (95%CI, 20.2%, 36.1%)) and shrimp (71.57% (95%CI, 61.3%, 80.1%)). In 35.11% (95%CI, 27.2%, 43.9%) of initial reactions to fish and 36.84% (27.4%, 47.4%) of reactions to shellfish, the symptoms were moderate/severe. Only 2.3% (95%CI, 0.6%, 7.1%) and 9.5% (95%CI, 4.7%, 17.6%) of all initial reactions were treated with epinephrine. Among those with fish allergy, 66.4% (95%CI, 57.5%, 74.3%) had eczema and 37.5% (95%CI, 29.2%, 46.5%) had asthma versus 45.7% (95%CI, 35.5%, 56.3%) and 42.6% (95%CI, 32.5%,53.2%) with shellfish allergy.ConclusionsSeafood allergies occur at an early age, mainly to salmon and shrimp. Epinephrine is severely underutilized. RationaleTo characterize initial allergic reactions to seafood (fish and shellfish) in children. To characterize initial allergic reactions to seafood (fish and shellfish) in children. MethodsCharts of children diagnosed with seafood allergy between 1991 and 2011 (based on history and positive skin test /elevated fish-specific IgE) at the Montreal Children's Hospital were reviewed. Subjects with unclear history or resolved allergy were excluded. Data was collected on clinical characteristics of the initial reaction, culprit food, demographics and history of atopy. Reactions involving the gastrointestinal/respiratory/ cardiovascular systems were defined as moderate/severe. Charts of children diagnosed with seafood allergy between 1991 and 2011 (based on history and positive skin test /elevated fish-specific IgE) at the Montreal Children's Hospital were reviewed. Subjects with unclear history or resolved allergy were excluded. Data was collected on clinical characteristics of the initial reaction, culprit food, demographics and history of atopy. Reactions involving the gastrointestinal/respiratory/ cardiovascular systems were defined as moderate/severe. ResultsOne hundred and thirty-five fish and 95 shellfish allergic children were identified. Median age at initial reaction was 2.4 years for fish and 8.7 years for shellfish (interquartile range: 1.1, 4.2 and 4.3, 11.7 respectively). Reactions to fish and shellfish were more common in males, 60.3% (95%CI, 51.4%, 68.7%) and 55.8% (95%CI, 45.3%, 65.8%), respectively. Reactions occurred mostly after ingestion (94.7% (95%CI, 88.9%, 97.6%) and 92.6% (95%CI, 84.9%, 96.7%) respectively). The commonest fish and shellfish implicated were salmon (27.4% (95%CI, 20.2%, 36.1%)) and shrimp (71.57% (95%CI, 61.3%, 80.1%)). In 35.11% (95%CI, 27.2%, 43.9%) of initial reactions to fish and 36.84% (27.4%, 47.4%) of reactions to shellfish, the symptoms were moderate/severe. Only 2.3% (95%CI, 0.6%, 7.1%) and 9.5% (95%CI, 4.7%, 17.6%) of all initial reactions were treated with epinephrine. Among those with fish allergy, 66.4% (95%CI, 57.5%, 74.3%) had eczema and 37.5% (95%CI, 29.2%, 46.5%) had asthma versus 45.7% (95%CI, 35.5%, 56.3%) and 42.6% (95%CI, 32.5%,53.2%) with shellfish allergy. One hundred and thirty-five fish and 95 shellfish allergic children were identified. Median age at initial reaction was 2.4 years for fish and 8.7 years for shellfish (interquartile range: 1.1, 4.2 and 4.3, 11.7 respectively). Reactions to fish and shellfish were more common in males, 60.3% (95%CI, 51.4%, 68.7%) and 55.8% (95%CI, 45.3%, 65.8%), respectively. Reactions occurred mostly after ingestion (94.7% (95%CI, 88.9%, 97.6%) and 92.6% (95%CI, 84.9%, 96.7%) respectively). The commonest fish and shellfish implicated were salmon (27.4% (95%CI, 20.2%, 36.1%)) and shrimp (71.57% (95%CI, 61.3%, 80.1%)). In 35.11% (95%CI, 27.2%, 43.9%) of initial reactions to fish and 36.84% (27.4%, 47.4%) of reactions to shellfish, the symptoms were moderate/severe. Only 2.3% (95%CI, 0.6%, 7.1%) and 9.5% (95%CI, 4.7%, 17.6%) of all initial reactions were treated with epinephrine. Among those with fish allergy, 66.4% (95%CI, 57.5%, 74.3%) had eczema and 37.5% (95%CI, 29.2%, 46.5%) had asthma versus 45.7% (95%CI, 35.5%, 56.3%) and 42.6% (95%CI, 32.5%,53.2%) with shellfish allergy. ConclusionsSeafood allergies occur at an early age, mainly to salmon and shrimp. Epinephrine is severely underutilized. Seafood allergies occur at an early age, mainly to salmon and shrimp. Epinephrine is severely underutilized." @default.
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• W1988948234 date "2012-02-01" @default.
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• W1988948234 title "Initial Allergic Reactions to Fish and Shellfish in Children: Clinical Characteristics and Treatment" @default.
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