FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988967653> ?p ?o ?g. }

• W1988967653 endingPage "131" @default.
• W1988967653 startingPage "121" @default.
• W1988967653 abstract "Glycerophospholipids are known to be hydrolyzed in the intestinal lumen into free fatty acids and lysophospholipids that are then absorbed by the intestinal epithelial cells. A monolayer of enterocyte-differentiated Caco-2 cell is often used to assess the intestinal bioavailability of nutrients. In this study, we examined how differentiated Caco-2 cells process lysoglycerolipids such as lysophosphatidylcholine (LPC). Our findings were twofold. (1) Caco-2 cells secreted both a lysophospholipase A-like enzyme and a glycerophosphocholine-phosphodiesterase enzyme into the apical, but not basolateral, lumen, suggesting that food-derived LPC is converted to a free fatty acid, sn-glycerol-3-phosphate, and choline through two sequential enzymatic reactions in humans. The release of the latter enzyme was differentiation-dependent. (2) Fatty acid-releasing activities toward exogenous fluorescent LPC, lysophosphatidic acid and monoacylglycerol were shown to be higher on the apical membranes of Caco-2 cells than on the basolateral membranes. These results suggest that human intestinal epithelial cells metabolize lysoglycerolipids by two distinct mechanisms involving secreted or apical-selective expression of metabolic enzymes." @default.
• W1988967653 created "2016-06-24" @default.
• W1988967653 creator A5003377360 @default.
• W1988967653 creator A5012445152 @default.
• W1988967653 creator A5019831374 @default.
• W1988967653 creator A5026459371 @default.
• W1988967653 creator A5032957138 @default.
• W1988967653 creator A5064446971 @default.
• W1988967653 creator A5081798809 @default.
• W1988967653 creator A5082977047 @default.
• W1988967653 creator A5088043964 @default.
• W1988967653 creator A5091525772 @default.
• W1988967653 date "2014-01-01" @default.
• W1988967653 modified "2023-10-16" @default.
• W1988967653 title "Extracellular metabolism-dependent uptake of lysolipids through cultured monolayer of differentiated Caco-2 cells" @default.
• W1988967653 cites W142918453 @default.
• W1988967653 cites W1495677738 @default.
• W1988967653 cites W1569915862 @default.
• W1988967653 cites W1610980198 @default.
• W1988967653 cites W1627716351 @default.
• W1988967653 cites W1904678284 @default.
• W1988967653 cites W1966684777 @default.
• W1988967653 cites W1969403767 @default.
• W1988967653 cites W1997298990 @default.
• W1988967653 cites W2001445237 @default.
• W1988967653 cites W2028738199 @default.
• W1988967653 cites W2029192296 @default.
• W1988967653 cites W2050817202 @default.
• W1988967653 cites W2055995527 @default.
• W1988967653 cites W2056879746 @default.
• W1988967653 cites W2065607376 @default.
• W1988967653 cites W2076872323 @default.
• W1988967653 cites W2082424812 @default.
• W1988967653 cites W2093152209 @default.
• W1988967653 cites W2100794767 @default.
• W1988967653 cites W2107992161 @default.
• W1988967653 cites W2115944543 @default.
• W1988967653 cites W2132163695 @default.
• W1988967653 cites W2137103352 @default.
• W1988967653 cites W2137233845 @default.
• W1988967653 cites W2149054264 @default.
• W1988967653 cites W2152335403 @default.
• W1988967653 cites W2159623504 @default.
• W1988967653 cites W2161343289 @default.
• W1988967653 cites W2399873710 @default.
• W1988967653 cites W2041899941 @default.
• W1988967653 doi "https://doi.org/10.1016/j.bbalip.2013.10.007" @default.
• W1988967653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24120920" @default.
• W1988967653 hasPublicationYear "2014" @default.
• W1988967653 type Work @default.
• W1988967653 sameAs 1988967653 @default.
• W1988967653 citedByCount "22" @default.
• W1988967653 countsByYear W19889676532014 @default.
• W1988967653 countsByYear W19889676532015 @default.
• W1988967653 countsByYear W19889676532016 @default.
• W1988967653 countsByYear W19889676532017 @default.
• W1988967653 countsByYear W19889676532018 @default.
• W1988967653 countsByYear W19889676532019 @default.
• W1988967653 countsByYear W19889676532020 @default.
• W1988967653 countsByYear W19889676532021 @default.
• W1988967653 countsByYear W19889676532022 @default.
• W1988967653 countsByYear W19889676532023 @default.
• W1988967653 crossrefType "journal-article" @default.
• W1988967653 hasAuthorship W1988967653A5003377360 @default.
• W1988967653 hasAuthorship W1988967653A5012445152 @default.
• W1988967653 hasAuthorship W1988967653A5019831374 @default.
• W1988967653 hasAuthorship W1988967653A5026459371 @default.
• W1988967653 hasAuthorship W1988967653A5032957138 @default.
• W1988967653 hasAuthorship W1988967653A5064446971 @default.
• W1988967653 hasAuthorship W1988967653A5081798809 @default.
• W1988967653 hasAuthorship W1988967653A5082977047 @default.
• W1988967653 hasAuthorship W1988967653A5088043964 @default.
• W1988967653 hasAuthorship W1988967653A5091525772 @default.
• W1988967653 hasConcept C1491633281 @default.
• W1988967653 hasConcept C170493617 @default.
• W1988967653 hasConcept C181199279 @default.
• W1988967653 hasConcept C185592680 @default.
• W1988967653 hasConcept C193176779 @default.
• W1988967653 hasConcept C195794163 @default.
• W1988967653 hasConcept C2776330855 @default.
• W1988967653 hasConcept C2776661833 @default.
• W1988967653 hasConcept C2777882243 @default.
• W1988967653 hasConcept C2778596009 @default.
• W1988967653 hasConcept C2778918659 @default.
• W1988967653 hasConcept C2779604457 @default.
• W1988967653 hasConcept C3018436504 @default.
• W1988967653 hasConcept C36020004 @default.
• W1988967653 hasConcept C41625074 @default.
• W1988967653 hasConcept C46721173 @default.
• W1988967653 hasConcept C543025807 @default.
• W1988967653 hasConcept C55493867 @default.
• W1988967653 hasConcept C8051207 @default.
• W1988967653 hasConcept C86803240 @default.
• W1988967653 hasConcept C95444343 @default.
• W1988967653 hasConceptScore W1988967653C1491633281 @default.
• W1988967653 hasConceptScore W1988967653C170493617 @default.
• W1988967653 hasConceptScore W1988967653C181199279 @default.
• W1988967653 hasConceptScore W1988967653C185592680 @default.

• next