FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1988982792> ?p ?o ?g. }

• W1988982792 endingPage "1312" @default.
• W1988982792 startingPage "1309" @default.
• W1988982792 abstract "Generation of oxidants has been implicated in lung injury and disease caused by a variety of inhaled agents such as ozone, particles, and mineral fibers. Antioxidants in the pulmonary system presumably provide the initial defense against such oxidants. We designed the present study to assess the oxidative and antioxidative capacity of alveolar macrophages (AM) from rats and hamsters. These two laboratory animal species commonly used in biomedical research are well known for their disparate response to pulmonary irritants/toxicants. AM from CD rats and Syrian golden hamsters were obtained by bronchoalveolar lavage. We assessed AM antioxidant levels by measuring the catalase and superoxide dismutase (SOD) activity and the intracellular concentrations of total glutathione, ascorbic acid, and alpha-tocopherol. We determined the AM oxidative capacity by assessing the ability of AM to oxidize extracellular glutathione (GSH) and to release superoxide anions. There were no significant differences in the intracellular antioxidant levels, except for catalase activity that was significantly (p < 0.05) higher in hamster AM than in rat AM. However, AM oxidative capacity was markedly different between the two species studied. The amount of spontaneous and phorbol myristate acetate (PMA)-induced GSH oxidation was about 5-fold higher in rat AM than in hamster AM, whereas the PMA-induced superoxide anion release did not differ significantly between the two rodents. In summary, our data suggest that species variation exists between the oxidative capacity of rat and that of hamster AM. Whereas the oxidative capacity of hamster AM appears to be based mainly on the formation of reactive oxygen species, it is suggested that rat AM possess an additional oxidative system." @default.
• W1988982792 created "2016-06-24" @default.
• W1988982792 creator A5003312143 @default.
• W1988982792 creator A5010735856 @default.
• W1988982792 creator A5019408836 @default.
• W1988982792 creator A5046528033 @default.
• W1988982792 creator A5046668482 @default.
• W1988982792 creator A5048453904 @default.
• W1988982792 date "1997-09-01" @default.
• W1988982792 modified "2023-09-30" @default.
• W1988982792 title "Interspecies comparison of rat and hamster alveolar macrophage antioxidative and oxidative capacity." @default.
• W1988982792 cites W191793640 @default.
• W1988982792 cites W1940436875 @default.
• W1988982792 cites W1964288597 @default.
• W1988982792 cites W1991001058 @default.
• W1988982792 cites W1991382935 @default.
• W1988982792 cites W2039395259 @default.
• W1988982792 cites W2039935804 @default.
• W1988982792 cites W2057453543 @default.
• W1988982792 cites W2074387820 @default.
• W1988982792 cites W2084247444 @default.
• W1988982792 cites W2132023106 @default.
• W1988982792 cites W2145916067 @default.
• W1988982792 cites W2160134111 @default.
• W1988982792 cites W2168178441 @default.
• W1988982792 cites W2172134825 @default.
• W1988982792 cites W2396212448 @default.
• W1988982792 cites W2411789354 @default.
• W1988982792 doi "https://doi.org/10.1289/ehp.105-1470122" @default.
• W1988982792 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1470122" @default.
• W1988982792 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9400743" @default.
• W1988982792 hasPublicationYear "1997" @default.
• W1988982792 type Work @default.
• W1988982792 sameAs 1988982792 @default.
• W1988982792 citedByCount "3" @default.
• W1988982792 countsByYear W19889827922014 @default.
• W1988982792 crossrefType "journal-article" @default.
• W1988982792 hasAuthorship W1988982792A5003312143 @default.
• W1988982792 hasAuthorship W1988982792A5010735856 @default.
• W1988982792 hasAuthorship W1988982792A5019408836 @default.
• W1988982792 hasAuthorship W1988982792A5046528033 @default.
• W1988982792 hasAuthorship W1988982792A5046668482 @default.
• W1988982792 hasAuthorship W1988982792A5048453904 @default.
• W1988982792 hasBestOaLocation W19889827921 @default.
• W1988982792 hasConcept C153911025 @default.
• W1988982792 hasConcept C181199279 @default.
• W1988982792 hasConcept C185592680 @default.
• W1988982792 hasConcept C202751555 @default.
• W1988982792 hasConcept C2775838275 @default.
• W1988982792 hasConcept C2776151105 @default.
• W1988982792 hasConcept C2778004101 @default.
• W1988982792 hasConcept C2778012055 @default.
• W1988982792 hasConcept C2778543330 @default.
• W1988982792 hasConcept C2778575167 @default.
• W1988982792 hasConcept C2778979269 @default.
• W1988982792 hasConcept C2779244956 @default.
• W1988982792 hasConcept C2779525107 @default.
• W1988982792 hasConcept C2780795997 @default.
• W1988982792 hasConcept C2986274086 @default.
• W1988982792 hasConcept C31903555 @default.
• W1988982792 hasConcept C48349386 @default.
• W1988982792 hasConcept C538909803 @default.
• W1988982792 hasConcept C55493867 @default.
• W1988982792 hasConcept C57600042 @default.
• W1988982792 hasConcept C86803240 @default.
• W1988982792 hasConceptScore W1988982792C153911025 @default.
• W1988982792 hasConceptScore W1988982792C181199279 @default.
• W1988982792 hasConceptScore W1988982792C185592680 @default.
• W1988982792 hasConceptScore W1988982792C202751555 @default.
• W1988982792 hasConceptScore W1988982792C2775838275 @default.
• W1988982792 hasConceptScore W1988982792C2776151105 @default.
• W1988982792 hasConceptScore W1988982792C2778004101 @default.
• W1988982792 hasConceptScore W1988982792C2778012055 @default.
• W1988982792 hasConceptScore W1988982792C2778543330 @default.
• W1988982792 hasConceptScore W1988982792C2778575167 @default.
• W1988982792 hasConceptScore W1988982792C2778979269 @default.
• W1988982792 hasConceptScore W1988982792C2779244956 @default.
• W1988982792 hasConceptScore W1988982792C2779525107 @default.
• W1988982792 hasConceptScore W1988982792C2780795997 @default.
• W1988982792 hasConceptScore W1988982792C2986274086 @default.
• W1988982792 hasConceptScore W1988982792C31903555 @default.
• W1988982792 hasConceptScore W1988982792C48349386 @default.
• W1988982792 hasConceptScore W1988982792C538909803 @default.
• W1988982792 hasConceptScore W1988982792C55493867 @default.
• W1988982792 hasConceptScore W1988982792C57600042 @default.
• W1988982792 hasConceptScore W1988982792C86803240 @default.
• W1988982792 hasIssue "suppl 5" @default.
• W1988982792 hasLocation W19889827921 @default.
• W1988982792 hasLocation W19889827922 @default.
• W1988982792 hasLocation W19889827923 @default.
• W1988982792 hasOpenAccess W1988982792 @default.
• W1988982792 hasPrimaryLocation W19889827921 @default.
• W1988982792 hasRelatedWork W164681620 @default.
• W1988982792 hasRelatedWork W1988982792 @default.
• W1988982792 hasRelatedWork W1993548188 @default.
• W1988982792 hasRelatedWork W2063379114 @default.
• W1988982792 hasRelatedWork W2124012982 @default.
• W1988982792 hasRelatedWork W2143075629 @default.

• next