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• W1988984975 abstract "Pretreatment with the catecholamine precursor L-DOPA but not the narcotic antagonist naloxone suppressed the tremorigenic effect of oxotremorine in mice. However, when animals were pretreated with both L-DOPA and several different doses of naloxone, there was a dose-related potentiation of the antitremor effect of L-DOPA. Naloxone also produced dose-dependent potentiation of the antitremor activity of lower doses of L-DOPA in the presence of the peripheral decarboxylase inhibitor carbidopa. These findings suggest a possible therapeutic application for naloxone in treatment of dopamine dysfunction disorders." @default.
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• W1988984975 date "1983-11-01" @default.
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• W1988984975 title "Potentiation by naloxone of the anti-oxotremorine effect of L-DOPA" @default.
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• W1988984975 doi "https://doi.org/10.1016/0014-2999(83)90634-9" @default.
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